DRSC/TRiP Functional Genomics Resources

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Protein Alignment HOXA5 and Dfd

DIOPT Version :9

Sequence 1:NP_061975.2 Gene:HOXA5 / 3202 HGNCID:5106 Length:270 Species:Homo sapiens
Sequence 2:NP_477201.1 Gene:Dfd / 40832 FlyBaseID:FBgn0000439 Length:586 Species:Drosophila melanogaster


Alignment Length:318 Identity:103/318 - (32%)
Similarity:134/318 - (42%) Gaps:81/318 - (25%)


- Green bases have known domain annotations that are detailed below.


Human     2 SSYFVNSFCGRYPNG-----PDYQLHNYGDHSSVSEQFRDSASMHS---GRYGYGYNGMDLS--- 55
            ||.:.|:....:|:.     |...|..|..|   :.:|..:.::||   ..||...|..:.|   
  Fly   128 SSNYANATPPSHPHSHPHAHPHQSLGYYVHH---APEFISAGAVHSDPTNGYGPAANVPNTSNGG 189

Human    56 -------------VGRSGSGHFGSGERARSYAASASAAPAEPRYSQPATSTHSPQPD-PLPCSAV 106
                         ||.|.:|::| |.......|:.|......:...|    ||...| ||.||:.
  Fly   190 GGGGSGAVLGGGAVGGSANGYYG-GYGGGYGTANGSVGSTHSQGHSP----HSQMMDLPLQCSST 249

Human   107 APSPGS----------------------------------DSHHGGKNSLSNSSGASADAGSTHI 137
            .|...:                                  |......:.:|.......|.....:
  Fly   250 EPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDEL 314

Human   138 SSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIG----GPEGKRA 198
            .|.:.......::.|....:|....:.          .|||||:|:|::....|    |.|.||.
  Fly   315 GSNDNDDDLGDSDSDEDLMAETTDGER----------IIYPWMKKIHVAGVANGSYQPGMEPKRQ 369

Human   199 RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKL 256
            ||||||:|.||||||||:||||||||||||||.|.|||||||||||||||||||||||
  Fly   370 RTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKL 427

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOXA5NP_061975.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 75..175 17/134 (13%)
Antp-type hexapeptide 176..181 4/4 (100%)
Homeobox 199..251 CDD:306543 46/51 (90%)
DfdNP_477201.1 Homeobox 370..422 CDD:278475 46/51 (90%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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