DRSC/TRiP Functional Genomics Resources

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Protein Alignment HOXA5 and pb

DIOPT Version :9

Sequence 1:NP_061975.2 Gene:HOXA5 / 3202 HGNCID:5106 Length:270 Species:Homo sapiens
Sequence 2:NP_476669.3 Gene:pb / 40826 FlyBaseID:FBgn0051481 Length:782 Species:Drosophila melanogaster


Alignment Length:253 Identity:82/253 - (32%)
Similarity:109/253 - (43%) Gaps:78/253 - (30%)


- Green bases have known domain annotations that are detailed below.


Human    48 GYNGMDLSVGRSGSGHFG-----SGERARSYAASASAAPAEPRY-----------SQPATS---T 93
            |..|:.:|||:.|.|..|     |.........:.....|:..|           |||:.:   .
  Fly    48 GVGGVGVSVGQPGIGQQGVPPVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLN 112

Human    94 H-SPQPDPLPCSAVAPSPGSDSHHGGKNSLSNSSGASADAG-STHISSREGVGTASGAEEDAPAS 156
            | ||:         :|..|:..          .|||....| :.:::...|||...|.....|..
  Fly   113 HLSPE---------SPKIGTPV----------GSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPDG 158

Human   157 SEQASAQSEPSPAPPAQPQIYPWMRKLHIS-----HDNIGG-------PEG---KRARTAYTRYQ 206
            .:..             |: ||||::...|     ::|.|.       ||.   :|.|||||..|
  Fly   159 MDSV-------------PE-YPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQ 209

Human   207 TLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK---------DNK 255
            .||||||||||:||.|.||||||.:|.|:|||:|:||||||||.|:         |||
  Fly   210 LLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNK 267

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOXA5NP_061975.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 75..175 19/115 (17%)
Antp-type hexapeptide 176..181 3/4 (75%)
Homeobox 199..251 CDD:306543 39/51 (76%)
pbNP_476669.3 COG5576 168..274 CDD:227863 50/100 (50%)
Homeobox 202..254 CDD:278475 39/51 (76%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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