Protein Alignment HOXA5 and exex

DIOPT Version :10

• Sequence 1: NP_061975.2
• Gene: HOXA5 / 3202
• HGNCID: 5106
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_648164.1
• Gene: exex / 38884
• FlyBaseID: FBgn0041156
• Length: 525
• Species: Drosophila melanogaster
• Alignment Length: 304
• Identity: 78/304 - (25%)
• Similarity: 105/304 - (34%)
• Gaps: 120/304 - (39%)

Human    70 ARSYAASASAAPAEPRYSQP----------ATSTH---SPQP----DPLPCSAVAPSPGSDSHH- 116
            :.|.|..|:.....|..|||          |.|.|   .|||    |.|.....|......:|.
  Fly   198 SHSGATMATTTLLPPAQSQPKKSFCIDALLAKSQHQSGEPQPIIVDDRLAALHYARDQAELNHAF 262

Human   117 -GGKNSLSNSSGASADAGSTHISSREGVGTASGAEE------------DAPASSEQASAQSEPS- 167
             ...|:.:.:..|::.||.  ||.:|.:.....:.|            ::|.||.::|....|.
  Fly   263 VTASNAAAAAQAAASAAGG--ISEQEALQRIRDSREYDSPSPDGMSRSESPTSSHRSSPPISPGC 325

Human   168 -------------------------------PAPPAQPQIYP-----------------WMRKLH 184
                                           |..|.:||.:|                 :.|.|.
  Fly   326 EDQQQPHGALHPQHLSMRMSDFHDEFKKPIPPHSPIRPQDFPLYAGGHPYQLLAQGGSAFHRPLD 390

Human   185 ISHDNIGGPEG--------------------------------------KRARTAYTRYQTLELE 211
            .|...|..|.|                                      :|.|||:|..|.||||
  Fly   391 PSGKPIPIPMGHNFMPSQLQFEFLARAGMLHHRIPELAAYPHHAILGKTRRPRTAFTSQQLLELE 455

Human   212 KEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 255
            |:|..|:||:|.:|.|:|..|.|||.|:||||||||||||:..|
  Fly   456 KQFKQNKYLSRPKRFEVASGLMLSETQVKIWFQNRRMKWKRSKK 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA5	NP_061975.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		30/162 (19%)
		Antp-type hexapeptide	176..181		1/21 (5%)
		Homeodomain	196..252	CDD:459649	35/55 (64%)
exex	NP_648164.1	Homeodomain	440..496	CDD:459649	35/55 (64%)