Protein Alignment HOXA5 and Dbx

DIOPT Version :10

• Sequence 1: NP_061975.2
• Gene: HOXA5 / 3202
• HGNCID: 5106
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 335
• Identity: 73/335 - (21%)
• Similarity: 112/335 - (33%)
• Gaps: 122/335 - (36%)

Human    20 QLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAASASAAPAEP 84
            |.|::..|..::......:..||..:.:.:.|       :|..||              ..||..
  Fly   204 QPHSHPQHQPLAVPGHQHSHPHSHHHHHHHPG-------AGHAHF--------------PHPAFL 247

Human    85 RYSQPATSTHSPQP-----------DPLPCSAVAPSPG-----SDSHHGGKNSLSNSSGASADAG 133
            .:..|....|..|.           .|...|: :.|||     ||::||...:..|.||    .|
  Fly   248 THQLPPHQHHQQQQHVQQQHPGNSCQPQTASS-SSSPGSTISDSDNNHGASTANGNGSG----TG 307

Human   134 STHISSREGVGTASGAEEDAPAS-----SEQASAQ-----------------SEPSPAPPAQPQI 176
            ::...:|......|..:||:.||     .:|...|                 ..|:|.||..|.:
  Fly   308 NSGQDARPHELANSNPDEDSSASRRLTQDKQQQQQLLGAGGTGGGGGGGHGHGHPTPPPPPPPPV 372

Human   177 ------------------------------------------------YPWMRKLHISHDNIGGP 193
                                                            :||      :|...|.|
  Fly   373 IAKPMPSRPTPFLPHTLNHPHLHSLLAHCRNPYMSVGAQVFPLPPGQGFPW------AHSTRGKP 431

Human   194 -EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLK 257
             .|...|..::..|...|||.|...:|:::..|.::|..|.|.:.|:|||||||||||:..   |
  Fly   432 RRGMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKWRNS---K 493

Human   258 SMSMAAAGGA 267
            ...:.|:||:
  Fly   494 ERELLASGGS 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA5	NP_061975.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		30/137 (22%)
		Antp-type hexapeptide	176..181		2/52 (4%)
		Homeodomain	196..252	CDD:459649	23/55 (42%)
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	23/53 (43%)