DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1637 and PAP24

DIOPT Version :9

Sequence 1:	NP_001285095.1	Gene:	CG1637 / 32019	FlyBaseID:	FBgn0030245	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_194219.2	Gene:	PAP24 / 828591	AraportID:	AT4G24890	Length:	615	Species:	Arabidopsis thaliana

Alignment Length:	446	Identity:	116/446 - (26%)
Similarity:	173/446 - (38%)	Gaps:	111/446 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 VTWSTRSLPPDQEVGAVSVVEYGQLVDGQVRLTQQARGKATKFVDGGHKQATQFIHRVTLRDLEP 120
            :.||.:.||..:............:..      ..|||...:  |.|      |.|...|::|.|
plant   203 IEWSAKGLPARRSPAGTLTFNRNSMCG------NPARGVGWR--DPG------FFHTSFLKELWP 253

  Fly   121 NATYSYHCGSDFG-----WSAIFQFRTVPSASVDWSPSLAIYGDMG------------------N 162
            |..|.|..|.|..     ||..:.|.:.|....|....:.|:||||                  |
plant   254 NREYIYRLGHDLVNGSTIWSKNYTFVSSPYPGQDSKQRVIIFGDMGKGERDGSNEYNDYQPGSLN 318

  Fly   163 ENAQSLARLQQETQRGMYDAIIHVGDFAYDMNTKNARVG--DEFMRQIETVAAYLPYMVVPGNHE 225
            ...|.:..|:.      .|.:.|:||..|    .|..:.  |:|..|::.:|:.:|||:..||||
plant   319 TTDQVIKDLKD------IDIVFHIGDLTY----SNGYLSQWDQFTAQVQPIASTVPYMIASGNHE 373

  Fly   226 EKF--NFSNYRARFSMPGG-----TENMFYSFDLGPVHFVGISTEVYYFLNYGLKPLVFQF---- 279
            ..:  ..|.|....|  ||     .|.|||........|       :|..:||:    |:|
plant   374 RDWPDTGSFYAGTDS--GGECGVPAETMFYFPAENRAKF-------WYKTDYGM----FRFCVAD 425

  Fly   280 ---EWLREDLAKANLPEN------RNKRPWIILYGHRPM-YCSNE-NDNDCTHSETLTRVGWPFV 333
               :| ||...:....||      |..:||:|...||.: |.:|: ...:.|..|.:.|.
plant   426 SEHDW-REGTEQYKFIENCLATVDRKTQPWLIFIAHRVLGYSTNDWYGKEGTFEEPMGRE----- 484

  Fly   334 HMFGLEPLLYEFGVDVAIWAHEHSYERLWPIYDYKVRN-------GTLKDSPYNDPSAPVHIVTG 391
               .|:.|..::.||:|.:.|.|:|||..|||:.:..|       ||.|.:        :|:|.|
plant   485 ---SLQKLWQKYKVDLAFYGHVHNYERTCPIYESQCVNNDKDHYSGTFKGT--------IHVVVG 538

  Fly   392 SAGCKEGREPFKGKIPEWSAFHSQDYGYTRLKAHNRTHIHFEQVSDDKNGAIIDDF 447
            .||  ....||...:|:||.....|:|:.:|.|.:.:.:.|| ......|.:.|.|
plant   539 GAG--SHLSPFSSLVPKWSLVRDYDFGFVKLTASDHSSLLFE-YKKSSTGQVYDSF 591

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1637	NP_001285095.1	PLN02533	20..449	CDD:215292	116/446 (26%)
		Pur_ac_phosph_N	38..142	CDD:293262	22/90 (24%)
		MPP_PAPs	149..451	CDD:277318	93/348 (27%)
PAP24	NP_194219.2	Pur_ac_phosph_N	172..278	CDD:293262	21/88 (24%)
		MPP_PAPs	286..595	CDD:277318	93/349 (27%)
		Metallophos	291..506	CDD:278574	63/246 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	97	1.000	Domainoid score	I2425
eggNOG	1	0.900	-	-		E1_COG1409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D426430at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X317
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.780