DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1637 and PAP22

DIOPT Version :9

Sequence 1:	NP_001285095.1	Gene:	CG1637 / 32019	FlyBaseID:	FBgn0030245	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_190850.2	Gene:	PAP22 / 824448	AraportID:	AT3G52820	Length:	434	Species:	Arabidopsis thaliana

Alignment Length:	474	Identity:	140/474 - (29%)
Similarity:	209/474 - (44%)	Gaps:	92/474 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FALLASLLLLVLL-------LPGIRSTPIDQDVDIVH-----YQPEQVHLSFGAERTDSEIVVTW 58
            |.|..|..||.|.       :|.:...| .:.:..||     ..|:|||:|...:   ..:.||:
plant     4 FGLFLSFTLLFLCPFISQADVPELSRQP-PRPIVFVHNDRSKSDPQQVHISLAGK---DHMRVTF 64

  Fly    59 STRSLPPDQEVGAVSVVEYGQ---LVDGQVRLTQQARGKATKFVDGGHKQATQFIHRVTLRDLEP 120
            .|.    |.:|  .||||||:   ..||      :|.|:.|.:....:|...  ||.|.:..|:.
plant    65 ITE----DNKV--ESVVEYGKQPGKYDG------KATGECTSYKYFFYKSGK--IHHVKIGPLQA 115

  Fly   121 NATYSYHCGSDFGWSAIFQFRTVPSASVDWSPSLAIYGDMGNE--NAQSLARLQQETQRGMYDAI 183
            |.||.|.||   |....|.|:|.||.   :....||.||:|..  .|.:|:.:..:.    ||..
plant   116 NTTYYYRCG---GNGPEFSFKTPPST---FPVEFAIVGDLGQTEWTAATLSHINSQD----YDVF 170

  Fly   184 IHVGDFAYDMNTKNARVGDEFMRQIETVAAYLPYMVVPGNHEEKF-------NFSNYRARFSMPG 241
            :..||.:|  ...:..:.|.|.|.:|.:|:..|:||..||||.:|       .|.:|.||:.||.
plant   171 LLPGDLSY--ADTHQPLWDSFGRLVEPLASKRPWMVTEGNHEIEFFPIIEHTTFKSYNARWLMPH 233

  Fly   242 ----GTENMFYSFDLGPVHFVGISTEVYYFLNYGLKPLVFQFEWLREDLAKANLPENRNKRPWII 302
                .|.|::||||:..||.|.:.:    :.::..:.  .|::||:.||||.    :|...||::
plant   234 TESFSTSNLYYSFDVAGVHTVMLGS----YTDFDCES--DQYQWLQADLAKV----DRKTTPWVV 288

  Fly   303 LYGHRPMYCSNENDNDCTHSETLTRVGWPFVHMFGLEPLLYEFGVDVAIWAHEHSYERLWPIYDY 367
            :..|.|.|.:||....  ..|::..         .:|.||:...|||....|.|:|||...:|:.
plant   289 VLLHAPWYNTNEAHEG--EGESMRE---------AMESLLFNARVDVVFSGHVHAYERFKRVYNN 342

  Fly   368 KVRNGTLKDSPYNDPSAPVHIVTGSAGCKEGRE-PFKGKIPEWSAFHSQDYGYTRLKAHNRTHIH 431
            |.           ||..|:||..|..|.:||.. .||......|.|....:|:.|||..:....|
plant   343 KA-----------DPCGPIHITIGDGGNREGLALSFKKPPSPLSEFRESSFGHGRLKVMDGKRAH 396

  Fly   432 FE-QVSDDKNGAIIDDFWL 449
            :. ..::|.|..:.|:.||
plant   397 WSWHRNNDSNSLLADEVWL 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1637	NP_001285095.1	PLN02533	20..449	CDD:215292	132/451 (29%)
		Pur_ac_phosph_N	38..142	CDD:293262	35/106 (33%)
		MPP_PAPs	149..451	CDD:277318	92/316 (29%)
PAP22	NP_190850.2	PLN02533	29..418	CDD:215292	133/449 (30%)
		Pur_ac_phosph_N	47..134	CDD:293262	35/106 (33%)
		MPP_PAPs	137..417	CDD:277318	93/320 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	151	1.000	Inparanoid score	I1702
OMA	1	1.010	-	-		QHG55026
OrthoDB	1	1.010	-	-		D426430at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2545
orthoMCL	1	0.900	-	-		OOG6_100704
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X317
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.740