DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1637 and acp7

DIOPT Version :9

Sequence 1:	NP_001285095.1	Gene:	CG1637 / 32019	FlyBaseID:	FBgn0030245	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_001092720.1	Gene:	acp7 / 571830	ZFINID:	ZDB-GENE-070615-9	Length:	443	Species:	Danio rerio

Alignment Length:	452	Identity:	240/452 - (53%)
Similarity:	310/452 - (68%)	Gaps:	33/452 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLLLVLLLPGIRSTPIDQDVDIVHYQPEQVHLSFGAERTDSEIVVTWSTRSLPPDQEVGAVSVVE 76
            ||||:.:.......||..       ||||||:|:..  ..:.::||||:.:...       ||||
Zfish    12 LLLLLCVCAVFADVPIGT-------QPEQVHISYPG--VQNSMLVTWSSANKTD-------SVVE 60

  Fly    77 YGQLVDGQVRLTQQARGKATKFVDGGHKQATQFIHRVTLRDLEPNATYSYHCGSDFGWSAIFQFR 141
            || |..|:: .:..|.|.::.|::.|.:....:||||.|.||.|.|:|.|||||..|||.:| |.
Zfish    61 YG-LWGGKL-FSHSATGNSSIFINEGAEYRVMYIHRVLLTDLRPAASYVYHCGSGAGWSELF-FF 122

  Fly   142 TVPSASVDWSPSLAIYGDMGNENAQSLARLQQETQRGMYDAIIHVGDFAYDMNTKNARVGDEFMR 206
            |..:.||.:||..|::||:||||.|||:|||:|||.|.||.|:|:||||||:...|.|:|||||:
Zfish   123 TALNESVFFSPGFALFGDLGNENPQSLSRLQKETQIGTYDVILHIGDFAYDLYEDNGRIGDEFMK 187

  Fly   207 QIETVAAYLPYMVVPGNHEEKFNFSNYRARFSMPGGTENMFYSFDLGPVHFVGISTEVY-YFLNY 270
            ||:::|||:|||..|||||..||||.|||||||||.||.::||:::||.|.:..||||| |:|.|
Zfish   188 QIQSIAAYVPYMTCPGNHEWAFNFSQYRARFSMPGDTEGLWYSWNVGPAHIISFSTEVYFYYLEY 252

  Fly   271 GLKPLVFQFEWLREDLAKANLPENRNKRPWIILYGHRPMYCSNENDNDCTHSETLTRVG------ 329
            ||..|..|:||||.||.:||.||||.:|||||..|||||||||::|:||||.::..|:|
Zfish   253 GLDLLFRQYEWLRADLQEANRPENRAERPWIITMGHRPMYCSNDDDDDCTHFQSYVRLGRNDTKP 317

  Fly   330 -WPFVHMFGLEPLLYEFGVDVAIWAHEHSYERLWPIYDYKVRNGTLKDSPYNDPSAPVHIVTGSA 393
             .|     |||.|.|::|||:.:|||||:||||||:|||||.||: .:.||.:|.|||||:||||
Zfish   318 PAP-----GLEELFYQYGVDLELWAHEHTYERLWPVYDYKVFNGS-SEEPYVNPKAPVHIITGSA 376

  Fly   394 GCKEGREPFKGKIPEWSAFHSQDYGYTRLKAHNRTHIHFEQVSDDKNGAIIDDFWLVKSKHG 455
            ||:|..:.|..|..:||||.|.|||||||:..|.||::.||||||:.|.:||...|||.|||
Zfish   377 GCREKHDGFIPKPRDWSAFRSTDYGYTRLQLINNTHLYLEQVSDDQYGKVIDQMTLVKEKHG 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1637	NP_001285095.1	PLN02533	20..449	CDD:215292	230/436 (53%)
		Pur_ac_phosph_N	38..142	CDD:293262	42/103 (41%)
		MPP_PAPs	149..451	CDD:277318	183/309 (59%)
acp7	NP_001092720.1	Pur_ac_phosph_N	31..123	CDD:293262	42/103 (41%)
		MPP_PAPs	132..434	CDD:277318	183/307 (60%)
		Metallophos	135..342	CDD:278574	126/211 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596907
Domainoid	1	1.000	278	1.000	Domainoid score	I1685
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23924
Inparanoid	1	1.050	474	1.000	Inparanoid score	I1459
OMA	1	1.010	-	-		QHG55026
OrthoDB	1	1.010	-	-		D331078at33208
OrthoFinder	1	1.000	-	-		FOG0003554
OrthoInspector	1	1.000	-	-		oto41571
orthoMCL	1	0.900	-	-		OOG6_100704
Panther	1	1.100	-	-	LDO	PTHR45867
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3332
SonicParanoid	1	1.000	-	-		X317
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.940