DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1637 and ACP7

DIOPT Version :9

Sequence 1:	NP_001285095.1	Gene:	CG1637 / 32019	FlyBaseID:	FBgn0030245	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_001004318.2	Gene:	ACP7 / 390928	HGNCID:	33781	Length:	438	Species:	Homo sapiens

Alignment Length:	444	Identity:	228/444 - (51%)
Similarity:	295/444 - (66%)	Gaps:	24/444 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLLLVLLLPGIRSTPIDQDVDIVHYQPEQVHLSFGAERTDSEIVVTWSTRSLPPDQEVGAVSVVE 76
            |||..|.:.|....|        ...|||||||:..|  ...:.|||:|       .|...|.|:
Human    14 LLLFSLGVQGSLGAP--------SAAPEQVHLSYPGE--PGSMTVTWTT-------WVPTRSEVQ 61

  Fly    77 YGQLVDGQVRLTQQARGKATKFVDGGHKQATQFIHRVTLRDLEPNATYSYHCGSDFGWSAIFQFR 141
            :|....|.:.|  :|:|....|||||..:...:|||||||.|.|...|.|.|||..|||..|:||
Human    62 FGLQPSGPLPL--RAQGTFVPFVDGGILRRKLYIHRVTLRKLLPGVQYVYRCGSAQGWSRRFRFR 124

  Fly   142 TVPSASVDWSPSLAIYGDMGNENAQSLARLQQETQRGMYDAIIHVGDFAYDMNTKNARVGDEFMR 206
            .:.:.: .|||.||::||:|.:|.:::.||:::||:|||||::|||||||:::..||||||.|||
Human   125 ALKNGA-HWSPRLAVFGDLGADNPKAVPRLRRDTQQGMYDAVLHVGDFAYNLDQDNARVGDRFMR 188

  Fly   207 QIETVAAYLPYMVVPGNHEEKFNFSNYRARFSMPGGTENMFYSFDLGPVHFVGISTEVYYFLNYG 271
            .||.|||.||||..||||||::|||||:|||||||..|.::||:||||.|.:..|||||:||:||
Human   189 LIEPVAASLPYMTCPGNHEERYNFSNYKARFSMPGDNEGLWYSWDLGPAHIISFSTEVYFFLHYG 253

  Fly   272 LKPLVFQFEWLREDLAKANLPENRNKRPWIILYGHRPMYCSNENDNDCTHSETLTRVGWPFVHMF 336
            ...:..||.||..||.|||  :||..|||||..|||||||||.:.:|||..|:..|.|.. ..::
Human   254 RHLVQRQFRWLESDLQKAN--KNRAARPWIITMGHRPMYCSNADLDDCTRHESKVRKGLQ-GKLY 315

  Fly   337 GLEPLLYEFGVDVAIWAHEHSYERLWPIYDYKVRNGTLKDSPYNDPSAPVHIVTGSAGCKEGREP 401
            |||.|.|::|||:.:||||||||||||||:|:|.||: ::.||.:|..||||:||||||:|...|
Human   316 GLEDLFYKYGVDLQLWAHEHSYERLWPIYNYQVFNGS-REMPYTNPRGPVHIITGSAGCEERLTP 379

  Fly   402 FKGKIPEWSAFHSQDYGYTRLKAHNRTHIHFEQVSDDKNGAIIDDFWLVKSKHG 455
            |......|||...::||||||...|.||||.:|||||::|.|:||.|:|:...|
Human   380 FAVFPRPWSAVRVKEYGYTRLHILNGTHIHIQQVSDDQDGKIVDDVWVVRPLFG 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1637	NP_001285095.1	PLN02533	20..449	CDD:215292	221/428 (52%)
		Pur_ac_phosph_N	38..142	CDD:293262	44/103 (43%)
		MPP_PAPs	149..451	CDD:277318	175/301 (58%)
ACP7	NP_001004318.2	Pur_ac_phosph_N	34..124	CDD:318794	41/100 (41%)
ACP7	NP_001004318.2	MPP_PAPs	131..429	CDD:277318	175/301 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	264	1.000	Domainoid score	I1933
eggNOG	1	0.900	-	-		E1_COG1409
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23924
Inparanoid	1	1.050	444	1.000	Inparanoid score	I1653
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55026
OrthoDB	1	1.010	-	-		D331078at33208
OrthoFinder	1	1.000	-	-		FOG0003554
OrthoInspector	1	1.000	-	-		oto89862
orthoMCL	1	0.900	-	-		OOG6_100704
Panther	1	1.100	-	-	LDO	PTHR45867
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3332
SonicParanoid	1	1.000	-	-		X317
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.870