DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1637 and papl-1

DIOPT Version :9

Sequence 1:	NP_001285095.1	Gene:	CG1637 / 32019	FlyBaseID:	FBgn0030245	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_001256452.1	Gene:	papl-1 / 179747	WormBaseID:	WBGene00008936	Length:	455	Species:	Caenorhabditis elegans

Alignment Length:	421	Identity:	171/421 - (40%)
Similarity:	244/421 - (57%)	Gaps:	34/421 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 PEQVHLSFGAERTDSEIVVTWSTRSLPPDQEVGAVSVVEYGQLVDGQVRLTQQARGKATKFVDGG 102
            |:|||:||..:.|  |:.|.|:|.|     ||.  ..|.||:...|   .|..|:|.:..:|.||
Worm    24 PDQVHISFTGDMT--EMAVVWNTFS-----EVS--QDVTYGKTGSG---ATSTAKGSSEAWVFGG 76

  Fly   103 HKQATQFIHRVTLRDLEPNATYSYHCGSDFGWSAIFQFRTVPSASVDWSPSLAIYGDMGNENAQS 167
               .|::.|:..:..||.:..|.|...     |..|.|:|:  ::...|..:.::||:|..:..|
Worm    77 ---ITRYRHKAIMTGLEYSTEYDYTIA-----SRKFSFKTL--SNDPQSYKVCVFGDLGYWHGNS 131

  Fly   168 LARLQQETQRGMYDAIIHVGDFAYDMNTKNARVGDEFMRQIETVAAYLPYMVVPGNHEEKF-NFS 231
            ...:.:....|.:|.|:|:||.|||::|.|.:|||.::...|.:.:.:||||:.||||:.: ||:
Worm   132 TESIIKHGLAGDFDFIVHLGDIAYDLHTNNGQVGDSYLNVFEPLISKVPYMVIAGNHEDDYQNFT 196

  Fly   232 NYRARFSMP--GGTENMFYSFDLGPVHFVGISTEVY-YFLNYGLKPLVFQFEWLREDLAKANLPE 293
            ||:.|||:|  |..:|.||||||||||:||:|||.| |:..||:.|::.|::||:.||..||  .
Worm   197 NYQKRFSVPDNGHNDNQFYSFDLGPVHWVGVSTETYGYYYEYGMDPVMTQYDWLKRDLTTAN--S 259

  Fly   294 NRNKRPWIILYGHRPMYCSNENDNDCTHSET-LTRVGWPFVHMFGLEPLLYEFGVDVAIWAHEHS 357
            ||...|||..:.|||.||||.|..:|...|. |.|.||  :.|.|||||..:..||...|.||||
Worm   260 NRAAHPWIFTFQHRPFYCSNVNSAECQSFENRLVRTGW--LDMPGLEPLFLQTSVDFGFWGHEHS 322

  Fly   358 YERLWPIYDYKVRNGTLKDSPYNDPSAPVHIVTGSAGCKEGREPFKGKIPEWSAFHSQDYGYTRL 422
            |||.:|:.|....|   ..:.|.:|.|||::::|||||......|..|...|||..:.|||::.:
Worm   323 YERFYPVADRAYWN---DPNAYINPKAPVYLISGSAGCHTPDALFTDKPWPWSAARNNDYGWSIV 384

  Fly   423 KAHNRTHIHFEQVSDDKNGAIIDDFWLVKSK 453
            ...|||||..||:|.|||...:||||::|.:
Worm   385 TVANRTHIRVEQISIDKNEQTVDDFWVIKDE 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1637	NP_001285095.1	PLN02533	20..449	CDD:215292	169/415 (41%)
		Pur_ac_phosph_N	38..142	CDD:293262	33/103 (32%)
		MPP_PAPs	149..451	CDD:277318	136/306 (44%)
papl-1	NP_001256452.1	Pur_ac_phosph_N	24..108	CDD:293262	33/103 (32%)
		MPP_PAPs	112..413	CDD:277318	136/307 (44%)
		Metallophos	116..323	CDD:278574	95/210 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I6072
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55026
OrthoDB	1	1.010	-	-		D331078at33208
OrthoFinder	1	1.000	-	-		FOG0003554
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100704
Panther	1	1.100	-	-	O	PTHR45867
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X317
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.930