Protein Alignment CG2186 and rbm33a

DIOPT Version :10

• Sequence 1: NP_001368978.1
• Gene: CG2186 / 32017
• FlyBaseID: FBgn0030243
• Length: 1193
• Species: Drosophila melanogaster
• Sequence 2: XP_009301673.1
• Gene: rbm33a / 100149667
• ZFINID: ZDB-GENE-140106-90
• Length: 1181
• Species: Danio rerio
• Alignment Length: 1358
• Identity: 303/1358 - (22%)
• Similarity: 467/1358 - (34%)
• Gaps: 443/1358 - (32%)

  Fly     5 NDDL-LNYELGDDIDDQALLGADEDELLLSDEELEKDV--TSEVKQQMRAEAE------------ 54
            :||| .::|.||.::|. .|.:.::...||||||..|:  :.|..|.:..:.|
Zfish    29 DDDLESDFEEGDLLEDD-WLSSKKNPSELSDEELNDDLLQSDEEDQNISGQGEAVSLNATLGMGT 92

  Fly    55 ------------------EWAQEQIRQHERKHKEQLQADATAATEVTVAATATAEVAPTLRAQPE 101
                              |..|....|..:...::.||               .:.....|.:..
Zfish    93 SVDFEDPGGYSGNAYKEGEGGQAGFSQDGQYEGDEYQA---------------VDEGFEYRGEQN 142

  Fly   102 LASSPAPDPVPAKPLVAQVEKHVDTAHAAVAAEPAKELVSASRSESPQQQAKEEAPPADCAEKEA 166
            ||  ...|.|    |..|:::.:|. ...|...|.:    ....|:.|||..||...|:  |:|.
Zfish   143 LA--VYQDEV----LDLQIDEPLDD-DFQVDEYPTE----YREQETNQQQVAEEEDEAN--EEET 194

  Fly   167 TQNNGNSEEQAENAGSQSEAERGLGLCSLLASSQESLPSASSASVISDPREDDEEREERTNYKTA 231
            .:.:.:...:.|.|.::::.|         |..::.    :.....||..|:|:|...|..:||
Zfish   195 EEQDSSHVTELEEADNENDLE---------AEHEQD----ADVKEESDEEEEDDEESGRLRFKT- 245

  Fly   232 SERSDNNL----------RQQQEHAHMS-------------PYQHQQRRLHGHGDKPRVGGGGRF 273
             ||.|:.:          |...|...:|             ..|.:|.|..|.|.....|.|||
Zfish   246 -ERKDDTVVRLSDVASKRRNIPETLELSKEAKADLQKFEENERQRKQGRFGGRGRGGPYGDGGR- 308

  Fly   274 MHGQQQQQQQQQSQMGKPPRGIGTRH--HLLRNPSPSFGIQQQRMGMAGMQPPPQRYGMPGNA-- 334
              |..|.:...:.:.|...||:|.|:  |:              .||.|.:..    |:.|..
Zfish   309 --GGMQGRGGMRGRGGAGGRGLGGRNDFHM--------------FGMGGFRGD----GVGGRGRI 353

  Fly   335 ----PPPQHLALMSTPVGAAPTAACLLPLTVPVTPLTLSIPQAHPSHQVHQQQQQTLSNPTFIPI 395
                ||     ||...:|        :...:.:||     |..|..||......::...|...|.
Zfish   354 NEQRPP-----LMQMNLG--------MQQQLRMTP-----PLQHHHHQSRLPGPRSSGGPGLFPD 400

  Fly   396 PGQYPATQP-----PNQSPQQAPTNTQQPHSAPASPLHTPTHSHMMHHSHNPNGGVLHHLLPH-- 453
            ||...|.||     |:.|.:.....|||.:|.|... |...:.|..|..|:|..   .|:.||
Zfish   401 PGTPIAQQPLQMLMPHMSHRSPGPRTQQLNSPPRHS-HAHPNQHQQHQQHHPKN---IHINPHFR 461

  Fly   454 --PHEQVRVGLLQPPPLAYAPNPGGYRNGALLGPG-PGPGLHQQHQSPHQQQSGMRPPL------ 509
              ....|:|..:  ||:...|.|.      :..|. ..|...|||      .....|||
Zfish   462 GPSSSPVQVPSM--PPVQNQPRPN------IASPRLSAPPDFQQH------LGNFGPPLRPLPSQ 512

  Fly   510 --YRNAPPSYGYDQGH----PPQHPQQFMRPHNGWRPQGDNARMQRPPLQTLPPHMMPGAPPNYA 568
              :|..||.:..||.|    .|:...|.|....|..|..:|:        .||  |....|||:.
Zfish   513 EPWRGPPPPHHQDQDHFFPGEPRFSGQHMFDQPGPAPLLNNS--------VLP--MSGQGPPNFP 567

  Fly   569 NGMGMRGP---PPQQQQSQQPPQQQPAPQQAGNPLQQAVNPGQPP--------QQPNGPPQQQGS 622
            ...|:.||   |....|:|.|  |..|.|.||        |..||        :||..|| |||.
Zfish   568 PQGGLGGPGFGPLGLGQNQGP--QSLALQHAG--------PPGPPGPRGFVGHRQPFSPP-QQGP 621

  Fly   623 SSVPRVSKVLINPNFKGGVEAATNKFIKE-THFMPAINSEAELLRQQVEFINKNRQYIEKRRMER 686
            ...|:        :...|::......::: .|..|.:..::  |.||.:   ::||.:..:.:..
Zfish   622 PFSPQ--------HMPFGMQVRQRGLLQQPLHHDPQLTHQS--LHQQHQ---QHRQDLPPQALLH 673

  Fly   687 SPPSSGSST-----------------GAASSG--------QAGERRRTRSRSRSRGRSYSPVKRV 726
            |.|.....|                 .:.|||        |..::|...:|.|.  ...||::::
Zfish   674 SQPPPQHQTHHQHHPRDQHLSQPHFRQSISSGHRQMQSRPQGNQQRNNHARPRM--TPPSPLQQI 736

  Fly   727 ERERERERERERDRERDRERDRERYGANRAAGNRGFRRASSRDRDENRGAASTASAQGAGGSASS 791
            ..:|                            |...|.......:.|           ...|..|
Zfish   737 PPQR----------------------------NSNLRELPIATSNNN-----------TCPSVPS 762

  Fly   792 GAAPPKRR-----------RSGSA--------GGGTARNPFSGEPR------GRPSETGSRSMPS 831
            |.|.|..:           |||.|        |.|:||.|.  :||      .:|:...|.:..:
Zfish   763 GQAKPVTKATQNVRQGPVARSGPAGKVGPLAQGQGSARAPL--QPRVPEIKKAQPAAQSSTTPQN 825

  Fly   832 -DEDEETRNYRLEIEKQKQLREKIMRDKELKRRRAAEEK-----------LHEEKRAEQHNTSP- 883
             |||||||.|||:||:||:|||:::|.|||:|::.|.|:           |..:.:..|:.|.|
Zfish   826 PDEDEETRQYRLKIEEQKRLREEVLRRKELRRQQQAGERKKELLERIGGQLPNQTQPTQNTTQPP 890

  Fly   884 -ARDDQEVAA--GQGSAA-PTPAASKHRPTASAGERKVISLKRRDDQDA-SSVRSRQAQGSQSNA 943
             |:..|.|.:  ..|:.. |:|..:..||..   :.::::.|.:..... |..:..|:.|..:|.
Zfish   891 TAQPPQPVPSLISNGTPQNPSPIVNSPRPNV---KTRLLNTKPQAPASGWSGPQKPQSTGPNANL 952

  Fly   944 QAGQGQQQQQAARKQLTAAKIAPEAKRSITDHLAPSSKQHHHHHQQHHQTAAAPARTVVLGSGAV 1008
               |||.|              |..||:|    ||.:.|.             ||        |.
Zfish   953 ---QGQYQ--------------PLQKRTI----APQNTQR-------------PA--------AQ 975

  Fly  1009 AGGTPPKPRDKLRLGTPSDDEVELDYDDDDLLLDEEDRLLATPSPPPQKASSKRSATPEPLVVKR 1073
            ..|...||.:...||.|                               :...||:
Zfish   976 GVGAQTKPVEGHGLGQP-------------------------------QPGGKRT---------- 999

  Fly  1074 NHKAMRGGSSTSAPSFSSNQRRVVLK-PTSNGSSSSGGDQQQLSHSGRQRDRRRGGEDSALQRKG 1137
               .|:..:|..:|......|.|.|: ..::.|.|:...|||....||...::|.|.    .||.
Zfish  1000 ---VMQRTNSVESPQVPQKVRVVKLQGEQADASPSTAPSQQQQPPIGRPIPQQRLGP----IRKV 1057

  Fly  1138 GVGSVGGSSSSGSGGGIFDRLEKRVAVSGGGSSGGGGGSSHKQRSKA----PARIVLK 1191
            .:.:.|..:...:|.|:.:: ..|:.|.|.|...|......:|..:|    |:.:.::
Zfish  1058 TMATGGVQNQQQAGRGVTNQ-TNRLVVRGRGRGRGTNRLLTQQNPRAQDHQPSTVCIE 1114

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2186	NP_001368978.1	PHA03247	<323..629	CDD:223021	90/344 (26%)
rbm33a	XP_009301673.1	PHA03247	<401..861	CDD:223021	139/554 (25%)
		PRK12323	<953..>1076	CDD:481241	42/209 (20%)
		RRM_SF	1111..1177	CDD:409669	0/4 (0%)