Protein Alignment sofe and PRC1

DIOPT Version :9

• Sequence 1: NP_001285092.1
• Gene: sofe / 32016
• FlyBaseID: FBgn0030242
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: XP_011520489.1
• Gene: PRC1 / 9055
• HGNCID: 9341
• Length: 621
• Species: Homo sapiens
• Alignment Length: 548
• Identity: 141/548 - (25%)
• Similarity: 255/548 - (46%)
• Gaps: 68/548 - (12%)

  Fly    19 DELHAMWSRMFEPQACEDCLAR---LKDHVHTFYTDLRKETSDKEQGILNDIAVLRNEASGLRRL 80
            :.|..:|..:..|:  :..|.|   :|.|:......:..|....::.::..|:|.:.|.:.|...
Human    20 NHLREIWELIGIPE--DQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSE 82

  Fly    81 LHKAVDIGERPDDVPMEIWYIKLEK----YIEQLRKELVSRRAEIRELLHQQQQLCDELGEQPLS 141
            ||      ..|.....|...::|||    .:|.:||:...|:.|::.|..|.|:||:.|......
Human    83 LH------VEPFQEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPHYD 141

  Fly   142 LLADPLPLPEEMDPFREHLAQLRDQRVQRLRDMDELRQNIKRNIKLLELQLRTDSEKRLLNADNH 206
            :.:..:|..||::.||:|:..||:.:..|..:...:::.|...::.|:....|..|:.::..|..
Human   142 IDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSFERDVVCEDED 206

  Fly   207 KL--------TPYAYVRLQEMDKEFADQVQDLIDRIDEMRGKIECLWQRLRMTDEY--------- 254
            ..        |....:|..||.|...:.|      .:.:|.:|..||.||::.:|.
Human   207 AFCLSLENIATLQKLLRQLEMQKSQNEAV------CEGLRTQIRELWDRLQIPEEEREAVATIMS 265

  Fly   255 -AMRRVREATSYNQCTYDILREELERCQAMRQQNLIAFIEQLRIEINEWWDLSLKSTEERRRFTT 318
             :..:||:|          |:.|::|.:.::.||:...||.:|:|:.::||....|.|:|:.|..
Human   266 GSKAKVRKA----------LQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAP 320

  Fly   319 YYCDTQTEDVLEQFEKELDNLKEFYNSNRKIFELYANRGELWTRMEALEAKANDPNRFNNRGGQL 383
            :..:..||.:|:..:.|:..||.:|..::::||......|.|......|.||:|||||.||||.|
Human   321 FCAEDYTESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGNL 385

  Fly   384 LKEEKERKTIMSRLPKIDQQITELVQVYMSETHTPFLVHGVDILERMSADWERHRQSKKQPSAQK 448
            |||||:|..:...|||:::::...::::..|....|:|:|...:|.::..||.||..|::...::
Human   386 LKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQWEMHRLEKERAKQER 450

  Fly   449 --KDGSNTSGQMKPPMVPLTPNTQKSNRGIHGSTSSLKKTPTKA-NASTTAMSTGNLHKRRHP-- 508
              |:...|..:|.....|.||:   ..||:      ...||.|| ..:||.||....:....|
Human   451 QLKNKKQTETEMLYGSAPRTPS---KRRGL------APNTPGKARKLNTTTMSNATANSSIRPIF 506

  Fly   509 ---QHHNTNSPQPAAAAKRNLIASLECN 533
               .:|:..|..|.:.:|.  :|:..|:
Human   507 GGTVYHSPVSRLPPSGSKP--VAASTCS 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sofe	NP_001285092.1	MAP65_ASE1	36..598	CDD:281928	138/531 (26%)
PRC1	XP_011520489.1	MAP65_ASE1	37..601	CDD:281928	138/529 (26%)
		Glyco_hydro_77	260..>411	CDD:294464	51/160 (32%)
		Pol_alpha_B_N	413..>551	CDD:285602	33/131 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	213	1.000	Domainoid score	I2754
eggNOG	1	0.900	-	-		E1_KOG4302
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I3643
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55705
OrthoDB	1	1.010	-	-		D272248at2759
OrthoFinder	1	1.000	-	-		FOG0001893
OrthoInspector	1	1.000	-	-		otm40738
orthoMCL	1	0.900	-	-		OOG6_103576
Panther	1	1.100	-	-	O	PTHR19321
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3175
SonicParanoid	1	1.000	-	-		X857
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.870