Protein Alignment sofe and ASE1

DIOPT Version :9

• Sequence 1: NP_001285092.1
• Gene: sofe / 32016
• FlyBaseID: FBgn0030242
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_116582.1
• Gene: ASE1 / 854223
• SGDID: S000005584
• Length: 885
• Species: Saccharomyces cerevisiae
• Alignment Length: 630
• Identity: 139/630 - (22%)
• Similarity: 237/630 - (37%)
• Gaps: 170/630 - (26%)

  Fly    38 LARLKDHVHTFYTDLRKETSDKEQGILNDIAVLRNEASGLRRLLHKAVDIGERPDDVPMEIWYIK 102
            |.||:|::.:..|......|.||.  |..:....|||            |.|.|:...:..:.::
Yeast   224 LPRLRDYLKSLITLKHLIQSVKEN--LPGLTEADNEA------------IAEFPELSTLTAYLLQ 274

  Fly   103 LE----------KYIEQLRKELVSRRA-------------EIRELLHQQQQ-------------- 130
            :|          |:|...||:::...|             |:.::..::.:
Yeast   275 IENGKGDIGLSMKFIIDNRKDILKGSAFKTINEESVKHMNEVIKIYEEEYERRFKSVLTKKVSIS 339

  Fly   131 -LCDELGEQPLSLLADPLPLPEEMDPFREHLAQLRDQRVQRLRDMDELRQNIKRNIKLLELQLRT 194
             :|::|| .||:.|     :.|:.:              |.||...| .:|....|.    ....
Yeast   340 SICEQLG-TPLATL-----IGEDFE--------------QDLRSYGE-EENSTSEIP----NFHP 379

  Fly   195 DSEKRLLNADNHKLTPYAYVRLQEMDKEFADQVQDLIDRIDEMRGKIECLWQRLRMTDEYAMRRV 259
            ...:|:...|      ....:||.:.||.||:.:.|:::..:       ||.||:::.||....:
Yeast   380 VDRERMSKID------ITLEKLQAIHKERADKKRLLMEQCQK-------LWTRLKISQEYIKTFM 431

  Fly   260 REATSYNQCTYDILREELERCQAMRQQNLIAFIEQLRIEINEWWDLSLKSTEERRRFTTYY---- 320
            |..:|.:..:...:.:|:.|.:||:::.:...|.....:|.|.|.....|.|.|.:|...:
Yeast   432 RNNSSLSTESLGRISKEVMRLEAMKKKLIKKLISDSWDKIQELWRTLQYSEESRSKFIIVFEELR 496

  Fly   321 --CDTQTED--VLEQFEKELDNLKEFYNSNRKIFELYANRGELWTRMEALEAKANDPNRFNNRGG 381
              ..|..||  :||..|.||..|:|.....:.|.:|.::...|....|.||..:.|.:|..:|..
Yeast   497 NSATTLQEDELLLETCENELKRLEEKLTLYKPILKLISDFESLQEDQEFLERSSKDSSRLLSRNS 561

  Fly   382 Q--LLKEEKERKTIMSRLPKIDQQITELVQVYMSET----HTPFLVHGVDILERMSADWERHRQS 440
            .  ||.|||.||.|....|::   |.:| ::.:.|.    ..|||..|..:.|  :.|.::....
Yeast   562 HKILLTEEKMRKRITRHFPRV---INDL-RIKLEEADGLFDQPFLFKGKPLSE--AIDIQQQEIE 620

  Fly   441 KKQPSAQKKDGSNTSGQMKPPMVPLTPNTQKSNRGIHGSTSSLK--KTPTKANASTTAMSTG-NL 502
            .|.|..:.:                   .|:|.:|..|:....|  |...||..|:..:..| ||
Yeast   621 AKYPRCRVR-------------------MQRSKKGKCGANKENKVIKNTFKATESSIRVPIGLNL 666

  Fly   503 HKRRHPQHHNTNSPQPAAAAKRNLIASLECNNASRKVC----VNGQKLLKSPQRK-VRVLEYSV- 561
            :..      |.....|:    :..|..|..|:.|::..    :.|...|.||.|: .|:|..:|
Yeast   667 NDA------NITYKTPS----KKTIQGLTKNDLSQENSLARHMQGTTKLSSPNRRATRLLAPTVI 721

  Fly   562 -RRGKGSGRPSTGSRN---------------------PQKIRPIP 584
             |..||:....|.:||                     |:::.|||
Yeast   722 SRNSKGNIERPTLNRNRSSDLSSSPRINHTHGEHAVKPRQLFPIP 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sofe	NP_001285092.1	MAP65_ASE1	36..598	CDD:281928	139/630 (22%)
ASE1	NP_116582.1	MAP65_ASE1	121..800	CDD:397896	139/630 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4302
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5674
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001893
OrthoInspector	1	1.000	-	-		otm46645
orthoMCL	1	0.900	-	-		OOG6_103576
Panther	1	1.100	-	-	LDO	PTHR19321
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3175
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.790