DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sofe and MAP65-9

DIOPT Version :9

Sequence 1:	NP_001285092.1	Gene:	sofe / 32016	FlyBaseID:	FBgn0030242	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	NP_001318863.1	Gene:	MAP65-9 / 836346	AraportID:	AT5G62250	Length:	549	Species:	Arabidopsis thaliana

Alignment Length:	607	Identity:	119/607 - (19%)
Similarity:	229/607 - (37%)	Gaps:	159/607 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KARILALTAEHFDELHAMWSRMFEPQA------------CEDCLARLKDHVHTFYTDLRKETSDK 59
            |::|.:..:....||..:|..:.|.:.            |.:...|..:.|......:::|.:|.
plant     3 KSQIESTWSSLLQELEIIWKEVGETETEREKILIEIEEECREVYNRKIEKVKEEKIRIKQEIADS 67

  Fly    60 EQGILNDIAVLR-----------NEASGLRRLLHKAVDIGERPDDVPMEIWYIKLEKYIEQLRKE 113
            |..:::..:|:.           ::.||..|.|         .|::      :|:.:.:|::.|.
plant    68 EARVIDICSVMEEPPILGRHHQSDQQSGNGRSL---------KDEL------VKILQKLEEMEKR 117

  Fly   114 LVSRRAEIRELLHQQQQLCDELG---------------EQPLSLLADPLPLPEEMDPFREHLAQL 163
            ...|:.:..:::...:.:.:|:.               |..|||        .:::.....|..|
plant   118 KSERKIQFIQVIDDIRCVREEINGESDDETCSSDFSADESDLSL--------RKLEELHRELYTL 174

  Fly   164 RDQRVQRLRDMDELRQNIKRNIKLLELQLR------------TDSEKRLLNADNHKLT----PYA 212
            ::|:..|::.:.:..:.::....:|.|..|            |:..:.:.|....||.    .:.
plant   175 QEQKRNRVKQIQDNIRTLESLCSVLGLNFRETVTKIHPSLVDTEGSRSISNETLDKLASSVQQWH 239

  Fly   213 YVRLQEMDKEFADQVQDLIDRIDEMRGKIECLWQRLRMTDEYAMR----------RVREATSYNQ 267
            ..::|.|     .::|||:..:.|       .|..:....|...:          .|.|.|..|.
plant   240 ETKIQRM-----QELQDLVTTMLE-------FWNLMDTPAEEQQKFMDVSCNIAATVSEITKPNS 292

  Fly   268 CTYDILRE---ELERCQAMRQQNLIAFIEQLRIEINEWW----------DLS----LKSTEERRR 315
            .:.|:|.|   ||.|.:.::...:...:.:.|.|:.|..          |::    :|:.|..
plant   293 LSIDLLEEVKAELCRLEELKWSKMKELVLKKRSELEEICRRTHIVLEEEDIAVENVIKAIESG-- 355

  Fly   316 FTTYYCDTQTEDVLEQFEKELDNLKEFYNSNRKIFE-----LYANRGELWTRMEALEAKANDPNR 375
                  |...|::|||.|.....:||...|.::|.|     |.|...|.|     ||....|.||
plant   356 ------DVNPENILEQIEYRAGKVKEEALSRKEILEKADKWLNACEEENW-----LEEYNQDENR 409

  Fly   376 FN-NRGGQL-LKEEKERKTIMSRLPKIDQQITELVQVYMSETHTPFLVHGVDILERMSADWERHR 438
            :| .:|..| ||..::.:.::::||.:.:.:...:.::.||....||..|..:|. |..::...|
plant   410 YNAGKGSHLILKRAEKARALVNKLPAMVEALASKITIWESEKEYEFLFDGNRLLS-MLEEYTELR 473

  Fly   439 QSKKQPSAQKKDGSNTSGQMKPPMVPLTPNTQKSNRGIHGSTSSLKKTPTKANASTTAMSTGNLH 503
            :.|:|...:|:|.....||:          |.:.::|......|.||   ....||......:.|
plant   474 EEKEQERRRKRDLKKHQGQV----------TSEQDKGSVTKPQSAKK---GLKVSTNKRFVSSPH 525

  Fly   504 KRRHPQHHNTNSPQPAAAAKRN 525
            .   ||   |:||.   :||.|
plant   526 T---PQ---TDSPH---SAKSN 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sofe	NP_001285092.1	MAP65_ASE1	36..598	CDD:281928	112/566 (20%)
MAP65-9	NP_001318863.1	MAP65_ASE1	50..547	CDD:397896	111/560 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I3425
eggNOG	1	0.900	-	-		E1_KOG4302
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2400
OMA	1	1.010	-	-		QHG55705
OrthoDB	1	1.010	-	-		D272248at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19321
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X857
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.070