DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sofe and MAP65-1

DIOPT Version :9

Sequence 1:	NP_001285092.1	Gene:	sofe / 32016	FlyBaseID:	FBgn0030242	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	NP_001190542.1	Gene:	MAP65-1 / 835616	AraportID:	AT5G55230	Length:	616	Species:	Arabidopsis thaliana

Alignment Length:	555	Identity:	112/555 - (20%)
Similarity:	207/555 - (37%)	Gaps:	127/555 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ACEDCLARLKDHVHTF---YTDLRKETSDKEQGILNDIAVLRNEASGLRRLLHKAVDIGERPDDV 94
            |.|....:.::.|..|   .:.::|...|...|:.|::.::......|::|           ||
plant   110 ALEQLWQQKEERVREFSDVQSQIQKICGDIAGGLSNEVPIVDESDLSLKKL-----------DD- 162

  Fly    95 PMEIWYIKLEKYIEQLRKELVSRRAEIRELLHQQQQLCDELGEQPLSLLADPLPLPEE------- 152
                    .:..:::|:||...|..::.|.:.....||..||...||.:.:..|..:|
plant   163 --------FQSQLQELQKEKSDRLRKVLEFVSTVHDLCAVLGLDFLSTVTEVHPSLDEDTSVQSK 219

  Fly   153 ------MDPFREHLAQLRDQRVQRLRDMDELRQNIKRNIKLLELQLRTDSEKRL-------LNAD 204
                  :....:.:..|:|.:.|||:.:.||...:   |.|..|....|.|:.|       :::.
plant   220 SISNETLSRLAKTVLTLKDDKKQRLQKLQELATQL---IDLWNLMDTPDEERELFDHVTCNISSS 281

  Fly   205 NHKLT-PYAYVRLQEMDKEFADQV---------------QDLIDRIDEMRGKIECLWQRLRMTDE 253
            ..::| |.|..|      :..:||               |.|:..|.....|.|....||   |:
plant   282 VDEVTVPGALAR------DLIEQVIYIALINLPMSSLRNQLLLANIHVKFVKAEVEVDRL---DQ 337

  Fly   254 YAMRRVREATSYNQCTYDILREELERCQAMRQQNLIAFIEQLRIEINEWWDLSLKSTEERRRFTT 318
            ....|::|.....|       .|||...|           :..:|:|.      :|..||.....
plant   338 LKASRMKEIAFKKQ-------SELEEIYA-----------RAHVEVNP------ESARERIMSLI 378

  Fly   319 YYCDTQTEDVLEQFEKELDNLKEFYNSNRKIFELYANRGELWTRMEALEAKA------NDPNRFN 377
            ...:.:..::|...:.::...||...|.:.|.:    |.|.|  |.|.|.::      .|.||::
plant   379 DSGNVEPTELLADMDSQISKAKEEAFSRKDILD----RVEKW--MSACEEESWLEDYNRDQNRYS 437

  Fly   378 -NRGGQL-LKEEKERKTIMSRLPKIDQQITELVQVYMSETHTPFLVHGVDIL----------ERM 430
             :||..| ||..::.:.::|::|.:...:....:.:..|....|...||.:|          :..
plant   438 ASRGAHLNLKRAEKARILVSKIPAMVDTLVAKTRAWEEEHSMSFAYDGVPLLAMLDEYGMLRQER 502

  Fly   431 SADWERHRQSKK---QPSAQKKDGSNT-SGQMKPPMVPLTPNTQKSNRGIHGSTSSLKKTPTKAN 491
            ..:..|.|:.||   ||..:::...:| ....:|.....|...:.:|.|.:|:.:.........|
plant   503 EEEKRRLREQKKVQEQPHVEQESAFSTRPSPARPVSAKKTVGPRANNGGANGTHNRRLSLNANQN 567

  Fly   492 AS-TTAMSTG---NLHKRRHPQHHNTNSPQPAAAA 522
            .| :||...|   .|::...|.::...|.:.||::
plant   568 GSRSTAKEAGRRETLNRPAAPTNYVAISKEEAASS 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sofe	NP_001285092.1	MAP65_ASE1	36..598	CDD:281928	110/552 (20%)
MAP65-1	NP_001190542.1	MAP65_ASE1	56..616	CDD:281928	112/555 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I3425
eggNOG	1	0.900	-	-		E1_KOG4302
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2400
OMA	1	1.010	-	-		QHG55705
OrthoDB	1	1.010	-	-		D272248at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR19321
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X857
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.980