Protein Alignment sofe and ase1

DIOPT Version :10

• Sequence 1: NP_572659.2
• Gene: sofe / 32016
• FlyBaseID: FBgn0030242
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_593523.1
• Gene: ase1 / 2543372
• PomBaseID: SPAPB1A10.09
• Length: 731
• Species: Schizosaccharomyces pombe
• Alignment Length: 644
• Identity: 141/644 - (21%)
• Similarity: 255/644 - (39%)
• Gaps: 148/644 - (22%)

  Fly    23 AMWSRMFEPQAC-----EDCLARLKDHVHTFYTDLRKETSDKEQGILNDIAVLRNEASGLRRLLH 82
            ||.:::.|.:.|     :||..|: |.:....:.|:         :.:|.:.|:.|:..::.|..
pombe    67 AMNAQLHEMEQCQKKLEDDCQQRI-DSIRFLVSSLK---------LTDDTSSLKIESPLIQCLNR 121

  Fly    83 KAVDIGERPDDVPMEIWYIKLEKYIEQLRKELVSRRAEIRELLHQQQQLCDELGEQPLSLLADPL 147
            .::..|:                |:.|..::|    :.|:|:.|:.:..|:.||        .|.
pombe   122 LSMVEGQ----------------YMAQYDQKL----STIKEMYHKLESYCNRLG--------SPF 158

  Fly   148 PLPEEMDPFREHLAQLRDQRVQRLRD-MDELRQNIKRNIKLL----ELQLRTDSEKRLLNAD--- 204
            .||:..:.|   |:.:.|...:.||. ::|..:.|...::::    |..|...||..:..||
pombe   159 VLPDFENSF---LSDVSDAFTESLRGRINEAEKEIDARLEVINSFEEEILGLWSELGVEPADVPQ 220

  Fly   205 ------NHKLTPY-AYVRLQEMD-----KE-FADQVQDLIDRIDEMRGKIECLWQRLRMTDEYAM 256
                  :|...|. .||..:.:|     || |:.:.:...|.:..::.::..||.:|:::.. ..
pombe   221 YEQLLESHTNRPNDVYVTQELIDQLCKQKEVFSAEKEKRSDHLKSIQSEVSNLWNKLQVSPN-EQ 284

  Fly   257 RRVREATSYNQCTYDILREELERCQAMRQQNLIAFIEQLRIEINEWWDLSLKSTEERRRFTTYYC 321
            .:..::::.||....:...|||:...:::::|..|:|..|.:|.:.||....|.|:|:.||..|.
pombe   285 SQFGDSSNINQENISLWETELEKLHQLKKEHLPIFLEDCRQQILQLWDSLFYSEEQRKSFTPMYE 349

  Fly   322 DTQTEDVLEQFEKELDNLKEFYNSNRKIFELYANRGELWTRMEALEAKANDPNRFNNRG----GQ 382
            |..||.||...|..:..|:...::|:....|......|....:.|||.:||.:|...||    |.
pombe   350 DIITEQVLTAHENYIKQLEAEVSANKSFLSLINRYASLIEGKKELEASSNDASRLTQRGRRDPGL 414

  Fly   383 LLKEEKERKTIMSRLPKIDQQITELVQVYMSETHTPFLVHGVDILERMSADWERHRQSKKQPSA- 446
            ||:|||.||.:...|||:...:...:..:.......||.:...:|:..        |...||.:
pombe   415 LLREEKIRKRLSRELPKVQSLLIPEITAWEERNGRTFLFYDEPLLKIC--------QEATQPKSL 471

  Fly   447 ---------QKKDGSNTSGQMKPP------MVPLTPNTQKSNRGIHGSTSSLKKTPTKANAS--- 493
                     :.|..:.|....:.|      .||.||:.:.::|.:....:.|.:.....|.|
pombe   472 YRSASAAANRPKTATTTDSVNRTPSQRGRVAVPSTPSVRSASRAMTSPRTPLPRVKNTQNPSRSI 536

  Fly   494 ----TTAMSTGNLHKRRHPQHHNTNSPQPAAAAKRNLIASLECNNASRKVCVNGQKLLKSPQRKV 554
                .:|.||.|   ||||           .|.:.::.|.|  |:|||....|
pombe   537 SAEPPSATSTAN---RRHP-----------TANRIDINARL--NSASRSRSAN------------ 573

  Fly   555 RVLEYSVRRGKG------SGRPSTGSRN------PQKIRPIPKIHVRPPSGEENESPDE 601
                 .:|:|..      |..|.:|:.|      |..:........:.|....:.:|.|
pombe   574 -----MIRQGANGSDSNMSSSPVSGNSNTPFNKFPNSVSRNTHFESKSPHPNYSRTPHE 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sofe	NP_572659.2	MAP65_ASE1	16..473	CDD:427641	111/495 (22%)
ase1	NP_593523.1	MAP65_ASE1	38..538	CDD:427641	115/520 (22%)
		Herpes_BLLF1	<476..723	CDD:282904	37/185 (20%)