Protein Alignment sofe and spd-1

DIOPT Version :10

• Sequence 1: NP_572659.2
• Gene: sofe / 32016
• FlyBaseID: FBgn0030242
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_490809.2
• Gene: spd-1 / 171683
• WormBaseID: WBGene00004952
• Length: 529
• Species: Caenorhabditis elegans
• Alignment Length: 528
• Identity: 109/528 - (20%)
• Similarity: 203/528 - (38%)
• Gaps: 137/528 - (25%)

  Fly   131 LCDEL--GEQPL------SLLAD-----PLPLPEEMDPFREHLAQLRDQRVQRLRDMDELRQNIK 182
            |||::  ||:.:      |:..|     .:.|..||:.| :..|:::|..:..:|       :::
 Worm    53 LCDDMLSGEKEMIHNLKVSIREDMQNVKKMRLELEMEDF-QRPAEIKDGSIALMR-------HLQ 109

  Fly   183 RNIKLLELQLRTDSE------------KRLLNAD------NHKLTP------------------- 210
            ..:|.||.:.:|..|            |:.|.:|      .|.|.|
 Worm   110 SEVKSLETEFQTRHEDQRVLIEKICNLKKRLESDFEFEYEIHALFPVKAFEKYSASCSEMEELLK 174

  Fly   211 YAYVRLQEMD------KEFADQVQDLIDRIDEMRGKIECLWQRLRMTDE----YAMRRVREATSY 265
            :.|.:::.:.      |..|..|.|.|...|:::..:|      :..|.    ::.|.:....||
 Worm   175 HRYHQIERLQTDISQWKSMAQNVADYIGGDDDLKNLLE------KNIDSPEFVFSERLLDSLQSY 233

  Fly   266 N---QCTYDILREELE-RCQAMRQQNLIAFIEQLRIEINEWWDLSLKSTEERRRFTTYYCDTQTE 326
            :   :..|....|::| |.....||            :.|.|:..|.|..:|.....:.....:|
 Worm   234 HSELEPLYKHWLEDIEFRWTEKHQQ------------LQELWEKCLVSEADRHYSPIFEPTKNSE 286

  Fly   327 DVLEQFEKELDNLKEFYNSNRKIFELYANRGELWTRMEALEAKANDPNRFNNRGGQLLKEEKERK 391
            ..|::.|.|.|.|::.|.:.|.:|||......:||....::.|...||.:...  .:|.:.|..:
 Worm   287 QTLKRMEDECDRLEKKYEACRIVFELVDKWRAVWTEKLTIDEKRKQPNYYKTT--NVLPDNKRER 349

  Fly   392 TIMSRLPKIDQQITELVQVYMSETH--TPFLVHGVDILERMSADWERHRQSKKQPSAQKKDGSNT 454
            .:::::|.::::|....:.|.:| |  ....:.|:..||.:....|.|::..|.....||:...
 Worm   350 ELLNQMPVLERKIDSAHRKYGNE-HDGEQISIQGMAPLEYVRFVQEEHKRELKFELQLKKEEKT- 412

  Fly   455 SGQMKPPMVPLTPNTQKSNRGIHGSTSSLKKTPTKANASTTAMSTGNLHKRRHPQHHNTNSPQPA 519
              :|:.|....||.|||         .::.:||         |||..:.......:.:|:.|...
 Worm   413 --RMQSPTPTRTPRTQK---------RAMFRTP---------MSTAKMEPVAKKLNFDTDLPPCM 457

  Fly   520 AAAKRNLIASLECNNASRKVCVNGQKLLKSPQRKVRVLEYSVRRGKGSGRPSTGSRNPQKIRPIP 584
            :.|...:|:.:   ..:|:..| |.| ..||:               ..:|||.| :.:...|:.
 Worm   458 SPATSEMISFI---TPTRRQAV-GPK-TSSPK---------------DTQPSTSS-SSRTTTPMS 501

  Fly   585 KIHVRPPS 592
            |..:.|.|
 Worm   502 KRAMTPSS 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sofe	NP_572659.2	MAP65_ASE1	16..473	CDD:427641	86/407 (21%)
spd-1	NP_490809.2	MAP65_ASE1	<228..427	CDD:427641	49/216 (23%)