DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2202 and Zfp800

DIOPT Version :9

Sequence 1:	NP_572657.2	Gene:	CG2202 / 32014	FlyBaseID:	FBgn0030240	Length:	889	Species:	Drosophila melanogaster
Sequence 2:	XP_006505206.1	Gene:	Zfp800 / 627049	MGIID:	1889334	Length:	715	Species:	Mus musculus

Alignment Length:	677	Identity:	128/677 - (18%)
Similarity:	203/677 - (29%)	Gaps:	234/677 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TPQPQPQLELGSCQEAQTEPAVSKLVS-QLEPLTTMDTVDAERVCRVCLKDVSLE---GELHFIF 63
            |..|....|..|..| |||..:.:..| ||:.:...||...|     .::..|:|   .|.....
Mouse   150 TDNPAEVTESSSTPE-QTEVQIQETSSEQLKAVPDADTEVEE-----AIEPPSIETVVDEAAAPT 208

  Fly    64 NETPVEQDANLARILDECTL-HQCERNDGMPPHMCSSCVEAARNAYRFKRHAERSYCSLVALL-- 125
            .|.|.|..|:| ...|...| ||.         :|..|.:...:....:||..:.:...:..|
Mouse   209 EEQPQESQADL-ETSDSSDLGHQL---------ICCLCRKEFNSRRGVRRHIRKVHKKKMEELKK 263

  Fly   126 ----GRSPQLKARGAEAASQTDQVAL-LPCEMCHDQFLNSLELRLHRNQVHR-------TTKEAT 178
                .::|...::|   .|::..|:| ..|.:|...|.....:|.|.::|||       |...||
Mouse   264 YIETRKTPNQSSKG---RSKSVLVSLSRSCPVCCKSFATKANVRRHFDEVHRGLRRDSITPDIAT 325

  Fly   179 SAG-----TDGLPSEDFKCKFCPQHFPHLRQLRSHLARSHEQTARLQCAHCQRTFSRRDHLLRHI 238
            ..|     ....|.:.||.:            :...:::.......:|..|:|.:|.:..|.||:
Mouse   326 KPGQPLFLDSASPKKSFKTR------------KQKSSKAEYNLTACKCLLCKRKYSSQIMLKRHM 378

  Fly   239 RNQHRDVEEDLLRTWPPADENTMNSDGGDELVSAEVLLNEEDNEDEVVGEAFQCNTNPISSNEDD 303
            :..|:...............||.|        |:||.:...|:.:          ::|.|.....
Mouse   379 QIVHKITLSGANSKREKGPNNTAN--------SSEVKVELADSVE----------SSPPSITHSP 425

  Fly   304 GEEANGANQTLWLHIKPEPCLEAEEVDLAMQLKLEKKRRRREKAEAQAETSIDRTVKNEHIAIGD 368
            ..|..|.|.:                              .||....|      |.||:
Mouse   426 QNELKGTNHS------------------------------NEKKNTPA------TQKNK------ 448

  Fly   369 SQFSIKEENQLVGSDDEAPMGVEDFMKLHVSGELPLSDEERFDGFADDDSDLDDDDDDDDEEDAG 433
                       |..|.|:|....
Mouse   449 -----------VKQDSESPKSAS------------------------------------------ 460

  Fly   434 DDDDGEFRLKQEPLDGEKPLKKAKSGRRRRRRNKDEPNPDNR---CEVCQRTFSRHCHLLRHKLS 495
                                ..|..|:::.|:.|.....|.:   |::|:|.|:...:|.:|...
Mouse   461 --------------------PSAAGGQQKTRKPKLSAGFDFKQLYCKLCKRQFTSKQNLTKHIEL 505

  Fly   496 HLE-----KKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCSLCEAAF---------------- 539
            |.:     .|.:.||.|.....|...:..|:..:|...........|:.
Mouse   506 HTDGNNIYVKFYKCPLCTYETRRKRDVIRHITVVHKKSSRYLGKITASLEIRAIKKPIDFVLNKV 570

  Fly   540 -----SRLDALERHKVSKHNGEGLEP---------GSELKL--QLAEHTCEYCSKRFSSKTYLRK 588
                 ||.:|  :|..||.:|....|         |.|:|:  ..:.|.|..|.|.|:.||||..
Mouse   571 AKRGPSREEA--KHNDSKQDGTSNSPSKKYEVADVGIEVKVTKNFSLHRCNKCGKAFAKKTYLEH 633

  Fly   589 HTLLH----TDFLYACKTCDETFRERA 611
            |...|    |:.....||...:.|.:|
Mouse   634 HKKTHKANATNSPEGNKTKGRSTRSKA 660

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2202	NP_572657.2	zf-AD	45..121	CDD:285071	16/79 (20%)
		C2H2 Zn finger	150..171	CDD:275368	5/20 (25%)
		C2H2 Zn finger	192..213	CDD:275370	0/20 (0%)
		C2H2 Zn finger	221..239	CDD:275370	7/17 (41%)
		COG5048	<443..730	CDD:227381	47/213 (22%)
		C2H2 Zn finger	476..496	CDD:275368	6/19 (32%)
		zf-H2C2_2	488..513	CDD:290200	7/29 (24%)
		C2H2 Zn finger	504..525	CDD:275368	5/20 (25%)
		C2H2 Zn finger	532..548	CDD:275368	4/36 (11%)
		C2H2 Zn finger	573..593	CDD:275368	9/19 (47%)
		C2H2 Zn finger	600..620	CDD:275368	4/12 (33%)
		zf-H2C2_2	613..637	CDD:290200
		C2H2 Zn finger	628..648	CDD:275368
		zf-H2C2_2	640..663	CDD:290200
		C2H2 Zn finger	656..676	CDD:275368
		C2H2 Zn finger	684..704	CDD:275368
		zf-C2H2	684..704	CDD:278523
		zf-H2C2_2	696..721	CDD:290200
		C2H2 Zn finger	712..732	CDD:275368
		C2H2 Zn finger	739..755	CDD:275368
Zfp800	XP_006505206.1	zf-C2H2_11	357..383	CDD:374679	7/25 (28%)
		zf-C2H2_assoc2	391..483	CDD:374681	27/224 (12%)
		C2H2 Zn finger	486..506	CDD:275370	6/19 (32%)
		C2H2 Zn finger	519..538	CDD:275370	5/18 (28%)
		C2H2 Zn finger	616..638	CDD:275369	10/21 (48%)
		zf-C2H2	616..638	CDD:333835	10/21 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910