DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2202 and ZBTB4

DIOPT Version :9

Sequence 1:NP_572657.2 Gene:CG2202 / 32014 FlyBaseID:FBgn0030240 Length:889 Species:Drosophila melanogaster
Sequence 2:NP_001122305.1 Gene:ZBTB4 / 57659 HGNCID:23847 Length:1013 Species:Homo sapiens


Alignment Length:461 Identity:104/461 - (22%)
Similarity:148/461 - (32%) Gaps:152/461 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   472 PDNRCEVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCSLCE 536
            ||.:|.                   |.::|..||.|.|:|.....|:.|        |.:|    
Human   223 PDLQCS-------------------LPRRPLPCPQCGKSFIHPKRLQTH--------EAQC---- 256

  Fly   537 AAFSRLDALERHKVSKHNGEGLEPGSELKLQLA------------EHTCEYCSKRFSSKTYLRKH 589
                |..|..|.......| |..||....:..:            ||..:               
Human   257 ----RRGASTRGSTGLGAG-GAGPGGPAGVDASALPPPVGFRGGPEHVVK--------------- 301

  Fly   590 TLLHTDFLYACKTCDETFRERAQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPY 654
             ::....||.|..|:.::...:.|:.|...|:.:|.:.|..|...||..:|...|...|.||:.|
Human   302 -VVGGHVLYVCAACERSYVTLSSLKRHSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWHTGERRY 365

  Fly   655 KCRFCVKAFPRATDLKVHERYHTGTKPNL--------------CNTCGKSFHRAYNLTIHMRTHT 705
            :|.||.:.|....:||.|:|...|..|.|              .||.     :.|.| :.||  .
Human   366 QCIFCWETFVTYYNLKTHQRAFHGISPGLLASEKTPNGGYKPKLNTL-----KLYRL-LPMR--A 422

  Fly   706 GERPYK-----CDQCPKSFTQSNDLKAHIRRH-------TGERYKCPHCDAYFLQLYNMRNHCMS 758
            .:||||     ..:.|.|.|.:......:...       ..|....|....:             
Human   423 AKRPYKTYSQGAPEAPLSPTLNTPAPVAMPASPPPGPPPAPEPGPPPSVITF------------- 474

  Fly   759 AHNK-----HIETKTGRLQRTGLLDDGGQ--SHLTTVVMPPARYPNELD-----PQLAAT----- 806
            ||..     |..:.:|. ..:|....||.  :.:.|...|| |.|.:.:     |:.|||     
Human   475 AHPAPSVIVHGGSSSGG-GGSGTASTGGSQAASVITYTAPP-RPPKKREYPPPPPEPAATPTSPA 537

  Fly   807 ---AAATAAGGAESTSSTTVIHSPG---------TYNATAAAPANTFDGANFTPT-AVNTPAPFG 858
               :.|||||.|   .:||...:.|         ||   .|.|.....|....|| |...|:...
Human   538 TAVSPATAAGPA---MATTTEEAKGRNPRAGRTLTY---TAKPVGGIGGGGGPPTGAGRGPSQLQ 596

  Fly   859 AFNFPP 864
            |   ||
Human   597 A---PP 599

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2202NP_572657.2 zf-AD 45..121 CDD:285071
C2H2 Zn finger 150..171 CDD:275368
C2H2 Zn finger 192..213 CDD:275370
C2H2 Zn finger 221..239 CDD:275370
COG5048 <443..730 CDD:227381 65/288 (23%)
C2H2 Zn finger 476..496 CDD:275368 1/19 (5%)
zf-H2C2_2 488..513 CDD:290200 7/24 (29%)
C2H2 Zn finger 504..525 CDD:275368 7/20 (35%)
C2H2 Zn finger 532..548 CDD:275368 3/15 (20%)
C2H2 Zn finger 573..593 CDD:275368 0/19 (0%)
C2H2 Zn finger 600..620 CDD:275368 4/19 (21%)
zf-H2C2_2 613..637 CDD:290200 7/23 (30%)
C2H2 Zn finger 628..648 CDD:275368 6/19 (32%)
zf-H2C2_2 640..663 CDD:290200 9/22 (41%)
C2H2 Zn finger 656..676 CDD:275368 8/19 (42%)
C2H2 Zn finger 684..704 CDD:275368 6/19 (32%)
zf-C2H2 684..704 CDD:278523 6/19 (32%)
zf-H2C2_2 696..721 CDD:290200 9/29 (31%)
C2H2 Zn finger 712..732 CDD:275368 3/19 (16%)
C2H2 Zn finger 739..755 CDD:275368 1/15 (7%)
ZBTB4NP_001122305.1 BTB 20..>62 CDD:279045
BTB 31..>62 CDD:197585
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 67..124
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 183..221
Interaction with CBFA2T3. /evidence=ECO:0000269|PubMed:23251453 186..348 34/176 (19%)
zf-C2HC_2 235..257 CDD:290624 9/37 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 257..281 7/24 (29%)
C2H2 Zn finger 311..331 CDD:275368 4/19 (21%)
zf-H2C2_2 323..347 CDD:290200 6/23 (26%)
C2H2 Zn finger 339..359 CDD:275368 6/19 (32%)
C2H2 Zn finger 367..385 CDD:275368 7/17 (41%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 428..766 43/196 (22%)
C2H2 Zn finger 728..748 CDD:275368
C2H2 Zn finger 767..787 CDD:275368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 783..852
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 883..904
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 972..1013
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24388
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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