DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2202 and Patz1

DIOPT Version :9

Sequence 1:	NP_572657.2	Gene:	CG2202 / 32014	FlyBaseID:	FBgn0030240	Length:	889	Species:	Drosophila melanogaster
Sequence 2:	NP_062520.1	Gene:	Patz1 / 56218	MGIID:	1891832	Length:	641	Species:	Mus musculus

Alignment Length:	382	Identity:	98/382 - (25%)
Similarity:	143/382 - (37%)	Gaps:	101/382 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   446 PLDGEK--PLKKAKSGRRRRRRNKDEPNPDNRCEVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCP 508
            |..||.  |:.:...|.|:|.|.:.:.    .||:|.:.|....||.||||||..:||::||.|.
Mouse   329 PRLGENGLPISEDPDGPRKRSRTRKQV----ACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCG 389

  Fly   509 KAFARSDHLKAHVQSLHS---NKEHKCSLCEAAFSRLDALERHKVSKHNGEGLEPGSELKLQLAE 570
            ..|.|.|.:..||:| |.   .|.:.|..|...|||.|.|..|....|..|            ..
Mouse   390 LRFKRKDRMSYHVRS-HDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSE------------RP 441

  Fly   571 HTCEYCSKRFSSKTYLRKHTLLHTDFLYACKTCDETFRERAQLREHEKTHT-GQRNFLCCIC--- 631
            |.|:.|:..|:::..||.|...|.|.: .|:.|.:..| .|.:.:|.|.|: |..|| |.||
Mouse   442 HKCQTCNASFATRDRLRSHLACHEDKV-PCQVCGKYLR-AAYMADHLKKHSEGPSNF-CSICNRE 503

  Fly   632 GDSFARNDYLRVHMRRHNGEKPYKCRFCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYN 696
            |...:..|.  :......|:           ...|:|||..|:
Mouse   504 GQKCSHQDL--IESSDSYGD-----------LSDASDLKTPEK---------------------- 533

  Fly   697 LTIHMRTHTGERPYKCD-QCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCMSAH 760
                   .:....:.|| ..||:..:|:..|         :|.||.|.::|.....:..|....|
Mouse   534 -------QSANGSFSCDVAVPKNKMESDGEK---------KYPCPECGSFFRSKSYLNKHIQKVH 582

  Fly   761 NKHIETKTGRL-----------QRTGLLDDGG----QSHLTTVVMPPARYPNELDPQ 802
            .:.:....|.|           |...||:..|    ||...:.::.|     |:|.|
Mouse   583 VRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDP-----EVDQQ 634

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2202	NP_572657.2	zf-AD	45..121	CDD:285071
		C2H2 Zn finger	150..171	CDD:275368
		C2H2 Zn finger	192..213	CDD:275370
		C2H2 Zn finger	221..239	CDD:275370
		COG5048	<443..730	CDD:227381	79/293 (27%)
		C2H2 Zn finger	476..496	CDD:275368	10/19 (53%)
		zf-H2C2_2	488..513	CDD:290200	14/24 (58%)
		C2H2 Zn finger	504..525	CDD:275368	9/20 (45%)
		C2H2 Zn finger	532..548	CDD:275368	7/15 (47%)
		C2H2 Zn finger	573..593	CDD:275368	6/19 (32%)
		C2H2 Zn finger	600..620	CDD:275368	6/19 (32%)
		zf-H2C2_2	613..637	CDD:290200	10/27 (37%)
		C2H2 Zn finger	628..648	CDD:275368	5/22 (23%)
		zf-H2C2_2	640..663	CDD:290200	1/22 (5%)
		C2H2 Zn finger	656..676	CDD:275368	5/19 (26%)
		C2H2 Zn finger	684..704	CDD:275368	0/19 (0%)
		zf-C2H2	684..704	CDD:278523	0/19 (0%)
		zf-H2C2_2	696..721	CDD:290200	4/25 (16%)
		C2H2 Zn finger	712..732	CDD:275368	6/20 (30%)
		C2H2 Zn finger	739..755	CDD:275368	4/15 (27%)
Patz1	NP_062520.1	BTB	30..159	CDD:306997
		C2H2 Zn finger	294..314	CDD:275368
		SFP1	<329..406	CDD:227516	31/81 (38%)
		C2H2 Zn finger	357..377	CDD:275368	10/19 (53%)
		zf-H2C2_2	369..394	CDD:316026	14/24 (58%)
		SFP1	<379..436	CDD:227516	21/57 (37%)
		C2H2 Zn finger	385..405	CDD:275368	9/20 (45%)
		C2H2 Zn finger	415..433	CDD:275368	8/17 (47%)
		zf-C2H2_6	442..467	CDD:316434	8/24 (33%)
		C2H2 Zn finger	444..464	CDD:275368	6/19 (32%)
		C2H2 Zn finger	470..489	CDD:275368	6/19 (32%)
		zf-C2H2_assoc3	492..558	CDD:318778	20/117 (17%)
		C2H2 Zn finger	561..582	CDD:275368	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000