DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2202 and CG11247

DIOPT Version :9

Sequence 1:	NP_572657.2	Gene:	CG2202 / 32014	FlyBaseID:	FBgn0030240	Length:	889	Species:	Drosophila melanogaster
Sequence 2:	NP_001097659.1	Gene:	CG11247 / 40414	FlyBaseID:	FBgn0037120	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	354	Identity:	111/354 - (31%)
Similarity:	176/354 - (49%)	Gaps:	38/354 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   417 DSDLDDDDDDDDEEDAGDDDDGEFRLKQEPLDGEKPLKKAKSGRRRRRRNKDEPNPDNRCEVCQR 481
            |:.:|:::||..|:|:.|||..:.:||          |.|:.|...:|::       :.|..|.:
  Fly    53 DACVDEEEDDGGEQDSKDDDYVQPQLK----------KSARKGEPVKRKH-------HVCSQCSK 100

  Fly   482 TFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSN-KEHKCSLCEAAFSRLDAL 545
            .|.....|.||.|.|.:::||.|..|.|::.::.:||.|:.:.|.: |:..||.|..:|:..:.|
  Fly   101 EFGGKTDLQRHMLIHSDERPHKCKDCGKSYRQAVNLKNHITTAHEHRKQFVCSQCPKSFALKERL 165

  Fly   546 ERHKVSKHNGEGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLH--TDF-LYACKTCDETF 607
            ..| :..|:||...|            |:.|.|:|:....|::|.:.|  |.. .:.|..|..:|
  Fly   166 RLH-MRLHSGEKPYP------------CDLCDKKFARGGQLQQHMVSHHKTSIQQFNCTKCSASF 217

  Fly   608 RERAQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHM-RRHNGEKPYKCRFCVKAFPRATDLKV 671
            ...|.||.|.:.|.......|.||.:.||....||.|: :.|:....::|..|.|......||..
  Fly   218 STNANLRVHMERHEQGMEHRCSICENQFANELALRAHINQEHHKLTQFECEICHKMIEPDEDLAT 282

  Fly   672 HERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGER 736
            |.:.||..|.::|..|...|.:.....:|||.|||||||:|..|.::|..|:.||.|||:||||:
  Fly   283 HMQRHTAVKTHVCEVCNTYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEK 347

  Fly   737 -YKCPHC--DAYFLQLYNMRNHCMSAHNK 762
             ::|..|  :..|.||.:::||....|.:
  Fly   348 PFRCQLCEDEVAFSQLAHLKNHMKKIHKQ 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2202	NP_572657.2	zf-AD	45..121	CDD:285071
		C2H2 Zn finger	150..171	CDD:275368
		C2H2 Zn finger	192..213	CDD:275370
		C2H2 Zn finger	221..239	CDD:275370
		COG5048	<443..730	CDD:227381	87/291 (30%)
		C2H2 Zn finger	476..496	CDD:275368	7/19 (37%)
		zf-H2C2_2	488..513	CDD:290200	10/24 (42%)
		C2H2 Zn finger	504..525	CDD:275368	6/20 (30%)
		C2H2 Zn finger	532..548	CDD:275368	5/15 (33%)
		C2H2 Zn finger	573..593	CDD:275368	6/19 (32%)
		C2H2 Zn finger	600..620	CDD:275368	7/19 (37%)
		zf-H2C2_2	613..637	CDD:290200	8/23 (35%)
		C2H2 Zn finger	628..648	CDD:275368	8/20 (40%)
		zf-H2C2_2	640..663	CDD:290200	7/23 (30%)
		C2H2 Zn finger	656..676	CDD:275368	6/19 (32%)
		C2H2 Zn finger	684..704	CDD:275368	6/19 (32%)
		zf-C2H2	684..704	CDD:278523	6/19 (32%)
		zf-H2C2_2	696..721	CDD:290200	13/24 (54%)
		C2H2 Zn finger	712..732	CDD:275368	9/19 (47%)
		C2H2 Zn finger	739..755	CDD:275368	5/17 (29%)
CG11247	NP_001097659.1	COG5048	<88..247	CDD:227381	49/178 (28%)
		C2H2 Zn finger	95..115	CDD:275368	7/19 (37%)
		zf-H2C2_2	107..132	CDD:290200	10/24 (42%)
		C2H2 Zn finger	123..144	CDD:275368	6/20 (30%)
		C2H2 Zn finger	152..172	CDD:275368	6/20 (30%)
		zf-H2C2_2	165..189	CDD:290200	10/36 (28%)
		C2H2 Zn finger	180..200	CDD:275368	6/19 (32%)
		COG5048	<192..369	CDD:227381	61/176 (35%)
		C2H2 Zn finger	210..230	CDD:275370	7/19 (37%)
		C2H2 Zn finger	238..260	CDD:275371	8/21 (38%)
		C2H2 Zn finger	267..287	CDD:275368	6/19 (32%)
		C2H2 Zn finger	295..315	CDD:275368	6/19 (32%)
		zf-H2C2_2	309..332	CDD:290200	13/22 (59%)
		C2H2 Zn finger	323..343	CDD:275368	9/19 (47%)
		C2H2 Zn finger	351..374	CDD:275368	7/22 (32%)
		C2H2 Zn finger	382..399	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I2264
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D42822at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.970