DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG2202 and Insm2

DIOPT Version :9

Sequence 1:NP_572657.2 Gene:CG2202 / 32014 FlyBaseID:FBgn0030240 Length:889 Species:Drosophila melanogaster
Sequence 2:XP_006240173.1 Gene:Insm2 / 314131 RGDID:1306949 Length:495 Species:Rattus norvegicus


Alignment Length:316 Identity:64/316 - (20%)
Similarity:94/316 - (29%) Gaps:98/316 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   476 CEVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQ------------------ 522
            |::|::.::....|.:|:.|.:.:..:.||.|.|.|:...:|.:|.:                  
  Rat   207 CQLCKQQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPTPACTASKPPHA 271

  Fly   523 -------SLHSNKEHKCSLCEAAFSRLDALERHKVSKHNGEGLEPGSEL--------------KL 566
                   ||.:.||:.| |.........|.:.....:|......||.:.              ::
  Rat   272 PLTPPDPSLAAGKENGC-LPRTEDQHPQARDSSGDGQHRDSAALPGLQALVHPEAARPQAPYSEV 335

  Fly   567 QLAEH----------------TCEYCSKRFSSKTYLRKHTLLHTDFLYACKTCDETFRERAQLRE 615
            .|..|                .|.||.|:|..:.|||||...|           ||...||....
  Rat   336 ILGRHGPRPSGASTGATSEVFVCPYCHKKFRRQAYLRKHLGTH-----------ETGSARATTPG 389

  Fly   616 HEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRFCVKAFPRATDLKVHERYHTGTK 680
            .....|....|.|.:||..|...|....|...|...:.......|.|                  
  Rat   390 FGSERTAPLTFACPLCGAHFPSADIREKHRLWHAVREELLLPALVGA------------------ 436

  Fly   681 PNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRR-HTGE 735
            |......|.|...|..:            :.|..||.:|..|..|..||.: |..|
  Rat   437 PTEAGPGGASEGSAQQI------------FSCKYCPSTFFSSPGLTRHINKCHPSE 480

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2202NP_572657.2 zf-AD 45..121 CDD:285071
C2H2 Zn finger 150..171 CDD:275368
C2H2 Zn finger 192..213 CDD:275370
C2H2 Zn finger 221..239 CDD:275370
COG5048 <443..730 CDD:227381 61/308 (20%)
C2H2 Zn finger 476..496 CDD:275368 4/19 (21%)
zf-H2C2_2 488..513 CDD:290200 8/24 (33%)
C2H2 Zn finger 504..525 CDD:275368 8/45 (18%)
C2H2 Zn finger 532..548 CDD:275368 3/15 (20%)
C2H2 Zn finger 573..593 CDD:275368 10/19 (53%)
C2H2 Zn finger 600..620 CDD:275368 4/19 (21%)
zf-H2C2_2 613..637 CDD:290200 6/23 (26%)
C2H2 Zn finger 628..648 CDD:275368 6/19 (32%)
zf-H2C2_2 640..663 CDD:290200 3/22 (14%)
C2H2 Zn finger 656..676 CDD:275368 2/19 (11%)
C2H2 Zn finger 684..704 CDD:275368 3/19 (16%)
zf-C2H2 684..704 CDD:278523 3/19 (16%)
zf-H2C2_2 696..721 CDD:290200 4/24 (17%)
C2H2 Zn finger 712..732 CDD:275368 8/20 (40%)
C2H2 Zn finger 739..755 CDD:275368
Insm2XP_006240173.1 C2H2 Zn finger 207..227 CDD:275368 4/19 (21%)
C2H2 Zn finger 235..255 CDD:275368 7/19 (37%)
zf-C2H2 356..378 CDD:278523 10/21 (48%)
C2H2 Zn finger 358..378 CDD:275368 10/19 (53%)
C2H2 Zn finger 402..422 CDD:275368 6/19 (32%)
C2H2 Zn finger 456..477 CDD:275368 8/20 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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