DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2202 and Fezf2

DIOPT Version :9

Sequence 1:	NP_572657.2	Gene:	CG2202 / 32014	FlyBaseID:	FBgn0030240	Length:	889	Species:	Drosophila melanogaster
Sequence 2:	NP_001100721.1	Gene:	Fezf2 / 305719	RGDID:	1311068	Length:	455	Species:	Rattus norvegicus

Alignment Length:	242	Identity:	84/242 - (34%)
Similarity:	123/242 - (50%)	Gaps:	23/242 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   493 KLSHL--EKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCSLCEAAFSRLDALERHKVSKHNG 555
            ||:.|  :|.||     |.::...:.|.|.::.:  .||:         |.|.| ||..|..|:
  Rat   212 KLASLTADKFPH-----PASYPHKERLHAPLEQV--LKEN---------SALTA-ERGGVKSHS- 258

  Fly   556 EGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFL-YACKTCDETFRERAQLREHEKT 619
              ..||.....:....|||.|.|.|::...|.:|..:||... :.||.|.:.||:.:.|..|:..
  Rat   259 --KLPGGSTDSKPKNFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKII 321

  Fly   620 HTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRFCVKAFPRATDLKVHERYHTGTKPNLC 684
            ||.::...|..||.:|.|:..|..|:|.|.|.||:.|.||.|.|.:..:.|.|:..|:|.|...|
  Rat   322 HTQEKPHKCNQCGKAFNRSSTLNTHIRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQYKC 386

  Fly   685 NTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRR 731
            ..|.|:||:.||||.||.||..::|:.|..|.|.|.::.|||.|:|:
  Rat   387 TICNKAFHQVYNLTFHMHTHNDKKPFTCATCGKGFCRNFDLKKHVRK 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2202	NP_572657.2	zf-AD	45..121	CDD:285071
		C2H2 Zn finger	150..171	CDD:275368
		C2H2 Zn finger	192..213	CDD:275370
		C2H2 Zn finger	221..239	CDD:275370
		COG5048	<443..730	CDD:227381	83/239 (35%)
		C2H2 Zn finger	476..496	CDD:275368	2/2 (100%)
		zf-H2C2_2	488..513	CDD:290200	7/21 (33%)
		C2H2 Zn finger	504..525	CDD:275368	3/20 (15%)
		C2H2 Zn finger	532..548	CDD:275368	4/15 (27%)
		C2H2 Zn finger	573..593	CDD:275368	7/19 (37%)
		C2H2 Zn finger	600..620	CDD:275368	7/19 (37%)
		zf-H2C2_2	613..637	CDD:290200	8/23 (35%)
		C2H2 Zn finger	628..648	CDD:275368	8/19 (42%)
		zf-H2C2_2	640..663	CDD:290200	11/22 (50%)
		C2H2 Zn finger	656..676	CDD:275368	7/19 (37%)
		C2H2 Zn finger	684..704	CDD:275368	11/19 (58%)
		zf-C2H2	684..704	CDD:278523	11/19 (58%)
		zf-H2C2_2	696..721	CDD:290200	12/24 (50%)
		C2H2 Zn finger	712..732	CDD:275368	9/20 (45%)
		C2H2 Zn finger	739..755	CDD:275368
Fezf2	NP_001100721.1	C2H2 Zn finger	274..294	CDD:275368	7/19 (37%)
		COG5048	<284..>390	CDD:227381	36/105 (34%)
		C2H2 Zn finger	302..322	CDD:275368	7/19 (37%)
		zf-H2C2_2	317..339	CDD:404364	7/21 (33%)
		C2H2 Zn finger	330..350	CDD:275368	8/19 (42%)
		C2H2 Zn finger	358..378	CDD:275368	7/19 (37%)
		SFP1	<380..436	CDD:227516	25/54 (46%)
		C2H2 Zn finger	386..406	CDD:275368	11/19 (58%)
		C2H2 Zn finger	414..432	CDD:275368	8/17 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100