DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2202 and znf-782

DIOPT Version :9

Sequence 1:	NP_572657.2	Gene:	CG2202 / 32014	FlyBaseID:	FBgn0030240	Length:	889	Species:	Drosophila melanogaster
Sequence 2:	NP_500033.1	Gene:	znf-782 / 190310	WormBaseID:	WBGene00021931	Length:	662	Species:	Caenorhabditis elegans

Alignment Length:	581	Identity:	142/581 - (24%)
Similarity:	216/581 - (37%)	Gaps:	152/581 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   406 DEERFDGFADDDSDLDDDDDDDDEEDAGDDDDGEFRL-----------------KQEPLDGEKPL 453
            :||.|:.:  :|..|:::::.|:|.:..::.|....|                 ...||..:.|.
Worm    25 EEEEFEEY--EDELLEEEEEFDEELEELENSDSASSLVSAGSPHGSSSSNGSHGSSPPLQVQSPS 87

  Fly   454 KKAKSGRRRRRRNKDEPNPDNR--CEVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDH 516
            :.:.|.      ......|:.|  |.||.:.||....|..||.||..:||:||..|.|.||:...
Worm    88 QGSGSS------GSPTGQPEKRHICTVCGKGFSYFSILESHKRSHTGEKPYNCHFCQKTFAQKAT 146

  Fly   517 LKAHVQSLHSNKEHKCSLCEAAFSRLDALERHKVSKHNGEGLEPGSELKLQLAEHTCEYCSKRFS 581
            |:.|.::....:.:||..||..|::......|:.|.|.|            :..:.|..|.|..|
Worm   147 LQVHERTHTGERPYKCRYCEKTFAQYGTKTVHEKSAHLG------------IRNYKCPKCDKLLS 199

  Fly   582 SKTYLRKHTLLHTDFLYACKTCDETFRERAQLREHEKT--HTGQRNFLCCICGDSFARNDYLRVH 644
            |.:.|..|...|.|..:.|..|.:||..:..|:.|.|.  ...:|..:|..|...||....|:||
Worm   200 SPSALYTHKKTHGDKTFRCDFCPKTFALKNYLKLHVKQVHEQNERKHVCVYCNKGFAYAGSLQVH 264

  Fly   645 MRRHNGEKPYKCRFCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGER- 708
            :|.|.||:||.|:||.|||....:|:.|||.|||.:|..|..|.::|.:...||.|..||..::
Worm   265 VRTHTGERPYVCKFCPKAFASQGNLQSHERTHTGERPYSCQFCQRTFIQKSQLTAHESTHLTQKH 329

  Fly   709 -------------------------PYKCDQCPKSFTQSNDLKAHIRRHTGE-RYKCPHCDAYFL 747
                                     .|:|..|.|.:..::.|..|:|:||.: .|.|..|...:.
Worm   330 SVNPDSTTADILPVAGSVTDHQMVGNYECTFCNKKYPYASSLYIHMRKHTEKSAYSCDGCGKPYS 394

  Fly   748 QLYNMRNH---CMSAHNKHIETKTGRLQRTGLLDDGGQSHLTTVVM------------------- 790
            |..::..|   |.:..|:   .||...|.:...|..|:|.:..:.:
Worm   395 QKISLNIHQDQCEAFKNR---LKTTDSQFSHNCDGCGKSFVQRIALQIHVDSCEPHKNLARLKLS 456

  Fly   791 -------------------------------------PPARY------PNELDPQLAATAAA--T 810
                                                 ||...      ||.|...|..|:..  |
Worm   457 QQQNQNQNSDSESDTEMKICPLPNPPLTLAPTHQQIPPPVNIYAQQPPPNPLGSILGNTSLTPQT 521

  Fly   811 AAGGAESTSSTTV----IHSPGTYNATAAAPANTFDGANFTPTAVNTPAPFGAFNFPPAVM 867
            ...|..|.||.:.    .|:|.|       |....:.|:|.|...:.|   .|..|.|:.|
Worm   522 LNFGLPSLSSASFSSLNAHAPFT-------PVELPNSADFGPLTASKP---HAVPFHPSEM 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2202	NP_572657.2	zf-AD	45..121	CDD:285071
		C2H2 Zn finger	150..171	CDD:275368
		C2H2 Zn finger	192..213	CDD:275370
		C2H2 Zn finger	221..239	CDD:275370
		COG5048	<443..730	CDD:227381	93/316 (29%)
		C2H2 Zn finger	476..496	CDD:275368	8/19 (42%)
		zf-H2C2_2	488..513	CDD:290200	12/24 (50%)
		C2H2 Zn finger	504..525	CDD:275368	7/20 (35%)
		C2H2 Zn finger	532..548	CDD:275368	4/15 (27%)
		C2H2 Zn finger	573..593	CDD:275368	7/19 (37%)
		C2H2 Zn finger	600..620	CDD:275368	7/21 (33%)
		zf-H2C2_2	613..637	CDD:290200	7/25 (28%)
		C2H2 Zn finger	628..648	CDD:275368	8/19 (42%)
		zf-H2C2_2	640..663	CDD:290200	13/22 (59%)
		C2H2 Zn finger	656..676	CDD:275368	10/19 (53%)
		C2H2 Zn finger	684..704	CDD:275368	6/19 (32%)
		zf-C2H2	684..704	CDD:278523	6/19 (32%)
		zf-H2C2_2	696..721	CDD:290200	9/50 (18%)
		C2H2 Zn finger	712..732	CDD:275368	6/19 (32%)
		C2H2 Zn finger	739..755	CDD:275368	3/15 (20%)
znf-782	NP_500033.1	C2H2 Zn finger	106..126	CDD:275368	8/19 (42%)
		zf-H2C2_2	119..143	CDD:290200	12/23 (52%)
		C2H2 Zn finger	134..154	CDD:275368	7/19 (37%)
		zf-H2C2_2	147..171	CDD:290200	7/23 (30%)
		C2H2 Zn finger	162..180	CDD:275368	5/17 (29%)
		COG5048	<187..404	CDD:227381	66/216 (31%)
		C2H2 Zn finger	191..211	CDD:275370	7/19 (37%)
		C2H2 Zn finger	218..239	CDD:275368	7/20 (35%)
		C2H2 Zn finger	248..268	CDD:275368	8/19 (42%)
		zf-H2C2_2	260..285	CDD:290200	15/24 (63%)
		C2H2 Zn finger	276..296	CDD:275368	10/19 (53%)
		zf-H2C2_2	288..313	CDD:290200	11/24 (46%)
		C2H2 Zn finger	304..324	CDD:275368	6/19 (32%)
		C2H2 Zn finger	386..403	CDD:275368	3/16 (19%)
		C2H2 Zn finger	424..441	CDD:275368	3/16 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000