DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2202 and si:ch211-261d7.6

DIOPT Version :9

Sequence 1:	NP_572657.2	Gene:	CG2202 / 32014	FlyBaseID:	FBgn0030240	Length:	889	Species:	Drosophila melanogaster
Sequence 2:	XP_017206987.1	Gene:	si:ch211-261d7.6 / 108179605	ZFINID:	ZDB-GENE-141216-266	Length:	1481	Species:	Danio rerio

Alignment Length:	1073	Identity:	207/1073 - (19%)
Similarity:	325/1073 - (30%)	Gaps:	399/1073 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 CRVCLKDVSLEGEL------HFIFNETPVEQDANLARILDEC-TLHQCERNDGMPPHMCSSCVEA 103
            |:||.|..|..|:.      |...:::...|.|:|.:...:| |..:|        :..:|.::|
Zfish   218 CKVCGKTYSTIGQCLNHERSHKQASKSVFHQIAHLKKKSFQCPTCGRC--------YSRASALDA 274

  Fly   104 ARNAYRFKRHAERSYCS--LVALLGRSPQLKARG--AEAASQTDQVAL----------------- 147
            .|..:..|....:::.:  .::|...|.|.:..|  :|...:.:|...
Zfish   275 HRRCHEVKLVKSKTFETEKTMSLNEASAQDQNNGTSSEQTEEQEQKVFQCFCGRSFRTMCGLGTH 339

  Fly   148 -------------------LPCEMCHDQFLNSLELRLHRNQVHRTTKEATSAGTDGLPSEDFKCK 193
                               ..|..|...|::|:.|..|: :.|:..::..      ..::.:||.
Zfish   340 QRFSTSCSDGKVKEEIKHPFVCSECGKTFISSVALLCHQ-RWHKRREQLV------CNNQSYKCS 397

  Fly   194 FCPQHFPHLRQLRSH--LARSHEQTAR-------------LQCAHCQRTFSRRDHLLRHIRNQHR 243
            .|.:.|..|.....|  ||.|.||.|:             .:|..|.|.|||...|..| :..|.
Zfish   398 ECGRVFTSLTFYNKHQRLAHSEEQAAKSFLHQVIQLKKKAFECQQCGRRFSRASALQSH-QLCHT 461

  Fly   244 DVEEDLLRTWPPADENTMNSDGGDELVSA-EVLLNEEDNEDEVVGEA------------FQCNT- 294
            |...|::...|             |:.:| ..:..:||:.|.||.:|            ..||.
Zfish   462 DAFFDIMEKKP-------------EMSTAIHTVKIQEDHVDSVVFQAQDISDVQVQEKDINCNNT 513

  Fly   295 ----NPIS--------SNEDDGEEANGANQTLWL------------------------------- 316
                |.:.        ::.||.|.....|..|.|
Zfish   514 VEEHNAVDADYEVVHITSSDDSESTQDPNPDLELVCESDQEEKDDLSLTAESTSSLPLNPAIDVK 578

  Fly   317 -------HIKPEPCLEAEEVD-------------------LAMQLK---LEKKRRRREKAE---- 348
                   |:..||.:.||.:.                   .|..|:   |..||..|:|||
Zfish   579 IVQIDYEHLNEEPFMNAELMSKSHPRVAKYNCPHCDRKFFKASSLRCHVLWHKRSMRKKAEWQKF 643

  Fly   349 -------------------------------------------AQAETSIDRTVKNEHIAIGDSQ 370
                                                       .|.|......:|.|...:..|:
Zfish   644 DILSPTKKVLLTCEVCGHESPSKSAHYFHMGKHDDKVACKSISYQLENLQKNNIKCEECGMCFSR 708

  Fly   371 FSIKEENQLVGSDDEAPM------------------------GVEDFMKLHVSGELPLSDEE--- 408
            .|....:|.:.|..:.|.                        |.:|.|..|.:....|...:
Zfish   709 LSALHSHQQLHSGKKKPFACLQCERSYATASGLYNHQKVCCGGAKDEMTKHFNPTKTLLGPKVHH 773

  Fly   409 ------------RFDGFADDDSDLDDDDDDDDEEDAGDDDDGEFRLKQEPLDGEKPLKKAKSGRR 461
                        .|.....::|:.  .|.:.....||..::|..|.|             |.|||
Zfish   774 CKKCGKGFWSMGAFCHHKQNNSEC--ADVETRPASAGATENGHIRRK-------------KRGRR 823

  Fly   462 RRRRNKDEPNP--DNRCEVCQRTFSRHCHLLRHKLSH------------------LEKKPHNCPH 506
            ...:.....|.  :::||||.:::......|:|||.|                  |:|..:.||.
Zfish   824 GGYKKVHPMNSKVEHKCEVCGKSYHMLACFLKHKLVHDAQGLRPAVKSFDYQVQQLKKNSYQCPD 888

  Fly   507 CPKAFARS----DHLKAH-------VQSLHSNKEHKCSLCEAAFSRLDALERHKVSKH------- 553
            |.|.|:|:    .|:|:|       |....|::..:|..|.:.|:....|:.|:  ||
Zfish   889 CGKVFSRAMALQFHMKSHGFETGLPVTDPGSSERPQCLTCYSFFASESLLQDHQ--KHCLKPEDN 951

  Fly   554 ---NGEGLEPGSELK---LQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKTCDETFRERAQ 612
               :.|..:.|:|::   .|.:|...|......|.|   .:.....::..|.||.|..:|.....
Zfish   952 VESSQEHEKVGTEIQDASSQKSEDVSEMSPSAVSDK---EQKAPSASNMKYKCKDCSRSFSVIGA 1013

  Fly   613 LREHEKTH---------------------------TGQRNFLCCICGDSFARNDYLRVHMRRHNG 650
            |..|::.|                           :.:..|:|..||..|..|..|..|.|.|..
Zfish  1014 LNFHKRIHRKGHQSKKMKSYPVKPLKLSKVKAEKCSAKSPFVCAECGRHFRTNSALGTHKRWHKD 1078

  Fly   651 EK--------------------PYKCRFCVKAFPRATDLKVHERYH-----TGTKPN-------- 682
            :|                    ||.|..|.|.|.....|:.|:.:|     ...|.|
Zfish  1079 KKFAKYLSKTNTVRSRKSMDGGPYLCNLCGKGFFYLCVLRRHQLHHPPMEAQPQKDNEVAESKDL 1143

  Fly   683 -LCNTCGKSFHRAYNLTIHMRTH---TGERPYKCDQCP-----KSFTQSNDLKAHI---RRHTGE 735
             .|..|..||.....||.|...|   ..|...:.:..|     ....||...||.|   .:...:
Zfish  1144 YTCPDCQMSFSTGSLLTTHFADHHSKNTETEKQSENVPTEELGSPIKQSYAYKADITKTEKTKVQ 1208

  Fly   736 RYKCPHCDAYFLQLYNMRNHCMSAHNKHIETKT 768
            .|:||||...||.:..:|.|....|:|..|..|
Zfish  1209 HYQCPHCPKSFLNIRGLRAHKWQKHDKVSEQAT 1241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2202	NP_572657.2	zf-AD	45..121	CDD:285071	17/83 (20%)
		C2H2 Zn finger	150..171	CDD:275368	6/20 (30%)
		C2H2 Zn finger	192..213	CDD:275370	7/22 (32%)
		C2H2 Zn finger	221..239	CDD:275370	8/17 (47%)
		COG5048	<443..730	CDD:227381	88/402 (22%)
		C2H2 Zn finger	476..496	CDD:275368	8/19 (42%)
		zf-H2C2_2	488..513	CDD:290200	12/42 (29%)
		C2H2 Zn finger	504..525	CDD:275368	10/31 (32%)
		C2H2 Zn finger	532..548	CDD:275368	4/15 (27%)
		C2H2 Zn finger	573..593	CDD:275368	3/19 (16%)
		C2H2 Zn finger	600..620	CDD:275368	6/19 (32%)
		zf-H2C2_2	613..637	CDD:290200	8/50 (16%)
		C2H2 Zn finger	628..648	CDD:275368	8/19 (42%)
		zf-H2C2_2	640..663	CDD:290200	10/42 (24%)
		C2H2 Zn finger	656..676	CDD:275368	6/19 (32%)
		C2H2 Zn finger	684..704	CDD:275368	7/19 (37%)
		zf-C2H2	684..704	CDD:278523	7/19 (37%)
		zf-H2C2_2	696..721	CDD:290200	6/32 (19%)
		C2H2 Zn finger	712..732	CDD:275368	6/27 (22%)
		C2H2 Zn finger	739..755	CDD:275368	7/15 (47%)
si:ch211-261d7.6	XP_017206987.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100