Protein Alignment CG2202 and znf853

DIOPT Version :10

• Sequence 1: NP_572657.2
• Gene: CG2202 / 32014
• FlyBaseID: FBgn0030240
• Length: 889
• Species: Drosophila melanogaster
• Sequence 2: XP_031748869.1
• Gene: znf853 / 100487314
• XenbaseID: XB-GENE-6031115
• Length: 604
• Species: Xenopus tropicalis
• Alignment Length: 528
• Identity: 153/528 - (28%)
• Similarity: 218/528 - (41%)
• Gaps: 79/528 - (14%)

  Fly   268 ELVSAEVLLNEEDNEDEVVGE-AFQCNTNPISSNEDDGEEANGANQTLWLHIKPEPCLEAEEVDL 331
            ||:|..:.|        :.|| |.:|....|..:.::.|...| ||.|...|..|.  |..:...
 Frog    97 ELISNIIQL--------LTGEVAIRCEDVSIYFSLEEWEYIKG-NQALLRKIMKEE--EEPQQVC 150

  Fly   332 AMQLKLEKKRR-----------RREKAEAQAETS---IDRTVKNEHIAIGDS---QFSIKEE--- 376
            ....:.|.||.           ..|.::..||.:   :|..::|..|:..:.   ...||||
 Frog   151 PPDGEYEDKREIPADLGGTLCYNNEPSKIGAEGADFCVDGELRNPEISPAEQPPPANGIKEEAAS 215

  Fly   377 --------NQLVGSDDEAP-MG-------VEDFMKLHVSGELPLSDEERFDGFADDDSDLDDDDD 425
                    .|:.|:|...| ||       .||:..:.:..|...|:.|. ......:|.:...|.
 Frog   216 DCSINPLTEQIQGTDTPTPIMGCSLNNNSAEDYRSVVIKEEESSSEGEN-QSDCSINSQIQGTDT 279

  Fly   426 DDDEEDAGDDDDGEFRLKQEPLDGEKPLKKAKSGRRRRRRNKDEPNPDNRCEVCQRTFSRHCHLL 490
            .....:..:..:...|.            |.|:|..:.::......| ..|.||::.|.....|.
 Frog   280 PTPNTETYNCSECHKRC------------KTKAGFLKHQKTHTGVKP-FVCSVCEKPFKYQSKLN 331

  Fly   491 RHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCSLCEAAFSRLDALERH-KVSKHN 554
            .||.||..:||.:|..|.|.|.|..||..|.::....|.:.||.|...||......|| ::.:
 Frog   332 LHKRSHTGEKPFSCSECGKRFTRHVHLIEHHRTHTGEKPYSCSDCGKHFSHSSDFYRHCRIHR-- 394

  Fly   555 GEGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTD-FLYACKTCDETFRERAQLREHEK 618
               ||     ||.:    |..|:|:|:|.:.|..|...|.. ..|.|..|.:.|...:||:.|.:
 Frog   395 ---LE-----KLCI----CSQCNKQFTSHSELIVHQSSHVGRGQYPCSECGKHFVSTSQLKIHLR 447

  Fly   619 THTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRFCVKAFPRATDLKVHERYHTGTKPNL 683
            .|:.:|.:.|..||..|..:.||.||.|.|.||||:.|..|.|.|.....|..|::.|||.||..
 Frog   448 VHSVERPYSCSECGKCFKYSSYLTVHKRIHTGEKPFTCTECGKGFIDRAYLNSHKKIHTGKKPFT 512

  Fly   684 CNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGER-YKCPHCDAYFL 747
            |..|||.|.....|..|.|.||||:|:.|.:|.|.|..|..||.|.|.||||: :.|..|..||:
 Frog   513 CTECGKCFSEGSRLKFHTRIHTGEKPFSCSECGKCFRNSTSLKFHTRIHTGEKPFACNECGKYFM 577

  Fly   748 QLYNMRNH 755
            ..|.:..|
 Frog   578 YRYQLTAH 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2202	NP_572657.2	zf-AD	45..121	CDD:214871
		C2H2 Zn finger	150..171	CDD:275368
		C2H2 Zn finger	192..213	CDD:275370
		C2H2 Zn finger	221..239	CDD:275370
		COG5048	<443..730	CDD:227381	98/288 (34%)
		C2H2 Zn finger	476..496	CDD:275368	7/19 (37%)
		C2H2 Zn finger	504..525	CDD:275368	8/20 (40%)
		C2H2 Zn finger	532..548	CDD:275368	5/15 (33%)
		C2H2 Zn finger	573..593	CDD:275368	7/19 (37%)
		C2H2 Zn finger	600..620	CDD:275368	6/19 (32%)
		C2H2 Zn finger	628..648	CDD:275368	9/19 (47%)
		C2H2 Zn finger	656..676	CDD:275368	6/19 (32%)
		C2H2 Zn finger	684..704	CDD:275368	8/19 (42%)
		C2H2 Zn finger	712..732	CDD:275368	9/19 (47%)
		C2H2 Zn finger	739..755	CDD:275368	5/15 (33%)
znf853	XP_031748869.1	KRAB_A-box	112..145	CDD:470626	9/35 (26%)
		COG5048	<265..502	CDD:227381	74/263 (28%)
		C2H2 Zn finger	289..309	CDD:275368	4/31 (13%)
		C2H2 Zn finger	317..337	CDD:275368	7/19 (37%)
		C2H2 Zn finger	345..365	CDD:275368	8/19 (42%)
		C2H2 Zn finger	373..393	CDD:275368	7/19 (37%)
		C2H2 Zn finger	401..421	CDD:275368	7/19 (37%)
		C2H2 Zn finger	429..449	CDD:275368	6/19 (32%)
		C2H2 Zn finger	457..477	CDD:275368	9/19 (47%)
		C2H2 Zn finger	485..505	CDD:275368	6/19 (32%)
		zf-H2C2_2	497..521	CDD:463886	11/23 (48%)
		C2H2 Zn finger	513..533	CDD:275368	8/19 (42%)
		zf-H2C2_2	525..550	CDD:463886	12/24 (50%)
		C2H2 Zn finger	541..561	CDD:275368	9/19 (47%)
		zf-H2C2_2	553..576	CDD:463886	10/22 (45%)
		C2H2 Zn finger	569..589	CDD:275368	6/17 (35%)