DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17333 and H6PD

DIOPT Version :9

Sequence 1:	NP_572656.1	Gene:	CG17333 / 32013	FlyBaseID:	FBgn0030239	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_001269516.1	Gene:	H6PD / 9563	HGNCID:	4795	Length:	802	Species:	Homo sapiens

Alignment Length:	241	Identity:	79/241 - (32%)
Similarity:	119/241 - (49%)	Gaps:	27/241 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SASEEQLVQALGDLLQRCSQEALAKHDKFSVGLSGGSLVQLLTKALKSCNLKTAKWVF------- 70
            ||..|:|:..|.:.::..:..|:.:..:|.:.|||||....|.:     .|.||.:.|
Human   568 SAWSEELISKLANDIEATAVRAVRRFGQFHLALSGGSSPVALFQ-----QLATAHYGFPWAHTHL 627

  Fly    71 FFCDERYVRLDDSDSTYGAYRAEWL--TQLPC-------IQESQFVRADTSQPLDACAADYEAKV 126
            :..|||.|.|.|.:|.:...:|..|  .::|.       :...|.:.|:..|.....|.:..|.|
Human   628 WLVDERCVPLSDPESNFQGLQAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALV 692

  Fly   127 KSQVDRFDLLLLGMGPDGHTCSLFPEQPATLQETKRLVIPIRNSPKPPPERITFTLPLINKARNV 191
            .:  ..|||:|||||.||||.||||:.|..| :.::||: :..||..|..|::.:|||||:|:.|
Human   693 AN--SSFDLVLLGMGADGHTASLFPQSPTGL-DGEQLVV-LTTSPSQPHRRMSLSLPLINRAKKV 753

  Fly   192 AFVVTGAAKASVVKSV--FVDLDKKFPAAWVNPTKGQLTLIVDAGA 235
            |.:|.|..|..:...|  .....||:|.:.|.|..|||...:|..|
Human   754 AVLVMGRMKREITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDA 799

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17333	NP_572656.1	Glucosamine_iso	14..228	CDD:279517	75/231 (32%)
H6PD	NP_001269516.1	Zwf	33..515	CDD:223441
		G6PD_N	40..222	CDD:278882
		G6PD_C	236..515	CDD:280876
		pgl	567..802	CDD:273494	79/241 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0363
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810