DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17333 and SOL4

DIOPT Version :9

Sequence 1:	NP_572656.1	Gene:	CG17333 / 32013	FlyBaseID:	FBgn0030239	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_011764.3	Gene:	SOL4 / 853163	SGDID:	S000003480	Length:	255	Species:	Saccharomyces cerevisiae

Alignment Length:	258	Identity:	85/258 - (32%)
Similarity:	128/258 - (49%)	Gaps:	40/258 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SEKKGALKVIPSASEEQLVQALGDLLQRCSQEALA--KHDKFSVGLSGGSLVQLLTKALKS---- 60
            ||||            .|:...|..:....:.||.  ....|::.:||||:.|.|.::|.:
Yeast     8 SEKK------------SLIHEFGKFILEKQESALTGDADAVFNIAISGGSMNQALYESLVNDKNI 60

  Fly    61 -CNLKTAKWVFFFCDERYVRLDDSDSTYGAYRAEWLTQLP-------------CIQESQFVRADT 111
             .::|..:|..||||||.|..:|..|.||.::...|..|.             .|.||.....:|
Yeast    61 FPHIKWPQWRIFFCDERLVPFEDPQSNYGQFKKTVLDPLVHQGNQLNLGPTVYTINESLIGGGET 125

  Fly   112 SQPLDACAADYEAKVKSQVDRFDLLLLGMGPDGHTCSLFP--EQPATLQETKRLVIPIRNSPKPP 174
            :.  ...|.:|.:.:.:.   |||:|||.|.|||||||||  |....::|..|.|:...||||.|
Yeast   126 AN--RKIAEEYASMLPAS---FDLILLGCGEDGHTCSLFPGVEFNYLVEEMDRKVLWCNNSPKAP 185

  Fly   175 PERITFTLPLINKARNVAFVVTGAAKASVVKSVFVDLDKKFPAAWVNPTKG-QLTLIVDAGAG 236
            .:||||||.::.:|::|.|:|.||||.:::..|.:..:.:.|:..||...| ::|..:|..||
Yeast   186 KDRITFTLAVVAEAKSVCFLVRGAAKKAIMHDVLIVKNSELPSVLVNEMVGTKVTWFLDDEAG 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17333	NP_572656.1	Glucosamine_iso	14..228	CDD:279517	77/236 (33%)
SOL4	NP_011764.3	NagB	2..252	CDD:223440	85/258 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341899
Domainoid	1	1.000	140	1.000	Domainoid score	I1029
eggNOG	1	0.900	-	-		E1_COG0363
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I1181
Isobase	1	0.950	-	0	Normalized mean entropy	S1649
OMA	1	1.010	-	-		QHG62685
OrthoFinder	1	1.000	-	-		FOG0001920
OrthoInspector	1	1.000	-	-		otm46852
orthoMCL	1	0.900	-	-		OOG6_101429
Panther	1	1.100	-	-	O	PTHR11054
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5
SonicParanoid	1	1.000	-	-		X1274
TreeFam	1	0.960	-	-
	15	14.740