DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Imp and RCF3

DIOPT Version :9

Sequence 1:	NP_001245616.1	Gene:	Imp / 32009	FlyBaseID:	FBgn0285926	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	NP_200118.3	Gene:	RCF3 / 835386	AraportID:	AT5G53060	Length:	652	Species:	Arabidopsis thaliana

Alignment Length:	506	Identity:	111/506 - (21%)
Similarity:	192/506 - (37%)	Gaps:	70/506 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 NPYPGMPGPGRQADFPLRILVQSEMVGAIIGRQGSTIRTITQQSRARVDVHRKENV-GSLEKSIT 192
            |..|....|...|....|||......|.:||:.|:.|::|.|.:.|.::||  |.| |..|:.|.
plant    54 NGRPSKSHPETMATTTYRILCHDAKAGGVIGKSGTIIKSIRQHTGAWINVH--ELVPGDAERIIE 116

  Fly   193 IYGN---------------PENCTNACKRILEVMQQEAI-------STNKGELSPECSEICLKIL 235
            |..|               .|...:...||||...|...       ..:.|.:.|....:..:::
plant   117 ISDNRRRDPDGRMPSFSPAQEALFSVHDRILESEAQFGYGGPPPEEEEDYGGVRPGGGRVVTRLV 181

  Fly   236 AHNNLIGRIIGKSGNTIKRIMQDTDTKITV----SSINDINSFNLERIITVKGLIENMSRAENQI 296
            .....:|.::||.|..|:::..:|.|.|.:    |::....|.: |.|:.:.|.:..:..|...:
plant   182 VSRMHVGCLLGKGGKIIEQMRIETKTHIRILPRESNLPRCVSLS-EEIVQIVGELNAVKNALAIV 245

  Fly   297 STKLRQSYENDLQ-------------AMAPQSLMFPGLHPMAMMSTPGNGMVFNTSMPFPSCQSF 348
            |::||:|...|..             |.|....| |.|...:....|......|.   |.|.||.
plant   246 SSRLRESQHRDRSNFQGRSHSPERSFAAAGDDYM-PQLRRQSSDRFPRGNFRNNN---FSSRQSN 306

  Fly   349 AMSKTPASVVPPVFPNDLQETTYLYI--PNNAVGAIIGTRGSHIRSIMRFSNASLKIAPLDADKP 411
            ...:.||   .||..|...|.....|  |.:.:..::|.....|..:.......::::     .|
plant   307 YAEEAPA---VPVGENVYSEELVFQILCPADKIVRVVGESQGIIDLLQNEIGVDVRVS-----DP 363

  Fly   412 LDQQTERKVTIVG--TPEGQ-WKAQYMIFEKMREEGFMCGTDDVRLTVELLVASSQVGRIIGKGG 473
            :....|:.:||..  .|:.. :.||..:.....:...:....|..:|..|||.|.....:.||.|
plant   364 VAGSDEQIITISSEEAPDDPFFPAQEALLHIQTQIIDLIPDKDNLITTRLLVPSRDSICLEGKAG 428

  Fly   474 QNVRELQRVTGSVIKLPEHALAPPSGGDEETPVHIIGLFYSVQSAQRRIRAMMLSTNPPPITKKQ 538
             :|.|:.|:||:.:::......|......:..:.|.|...:.:.|...:..::.|.....:::|:
plant   429 -SVSEISRLTGTSVQILAREEIPRCASINDVVIQITGEIRAAREALVELTLLLRSHMFKELSQKE 492

  Fly   539 -KAAKEQLQQQQQSLAG---AASSGSQQQQPQSPSQQQALPPQLHHQPVSS 585
             ..|........:.:||   .|||.:..|..:.|:..     .|:.|.||:
plant   493 TPPASTSTTGPLEGVAGVMEVASSNNTIQSREGPTSS-----NLNLQQVST 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Imp	NP_001245616.1	RRM	<37..>146	CDD:223796	4/16 (25%)
		RRM2_VICKZ	42..118	CDD:240805
		KH-I	145..208	CDD:238053	22/78 (28%)
		KH-I	232..296	CDD:238053	14/67 (21%)
		KH-I	369..436	CDD:238053	11/71 (15%)
		KH-I	455..522	CDD:238053	17/66 (26%)
RCF3	NP_200118.3	PCBP_like_KH	69..143	CDD:239089	21/75 (28%)
		PCBP_like_KH	179..246	CDD:239089	14/67 (21%)
		KH-I	326..395	CDD:320758	11/73 (15%)
		KH-I	410..477	CDD:320758	17/67 (25%)
		KH_1	578..641	CDD:306517
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D286875at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920