DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Imp and AT5G15270

DIOPT Version :9

Sequence 1:	NP_001245616.1	Gene:	Imp / 32009	FlyBaseID:	FBgn0285926	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	NP_197031.3	Gene:	AT5G15270 / 831379	AraportID:	AT5G15270	Length:	548	Species:	Arabidopsis thaliana

Alignment Length:	570	Identity:	128/570 - (22%)
Similarity:	234/570 - (41%)	Gaps:	128/570 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 KLHAEQLDKNQRRSQRNQRNPYPGMPGPGR-------------QADFPLRILVQSEMVGAIIGRQ 161
            ::..:..|.:::||:  .::.|....|..|             :.|...|.|...:.:|::|||.
plant     6 RMSPDHRDSHRKRSR--PQSDYDDNGGSKRRYRGDDRDSLVIDRDDTVFRYLCPVKKIGSVIGRG 68

  Fly   162 GSTIRTITQQSRARVDVHRKENV-GSLEKSITIYGNPENCTNAC---KRILEVMQQEAISTN--- 219
            |..::.:...:|:::.:  .|.: |..|:.|||| :|.:.|||.   :::|...|......:
plant    69 GDIVKQLRNDTRSKIRI--GEAIPGCDERVITIY-SPSDETNAFGDGEKVLSPAQDALFRIHDRV 130

  Fly   220 -----KGELSPEC-SEICLKILAHNNLIGRIIGKSGNTIKRIMQDTDTKITVSSINDIN----SF 274
                 :.|.|||. .::..|:|..::.||.|:|:.|..::.|..:|..:|.:  :.|.|    :.
plant   131 VADDARSEDSPEGEKQVTAKLLVPSDQIGCILGRGGQIVQNIRSETGAQIRI--VKDRNMPLCAL 193

  Fly   275 NLERIITVKGLIENMSRAENQISTKLRQSYENDLQAMAPQSLM-FPGLHPM-AMMSTPGNGMVFN 337
            |.:.:|.:.|.:..:.:|..||:::|   :||..::   |:|: ..|.:|. ::||..|...:..
plant   194 NSDELIQISGEVLIVKKALLQIASRL---HENPSRS---QNLLSSSGGYPAGSLMSHAGGPRLVG 252

  Fly   338 TSMPFPSCQSFAMSKTPASVVPPVFPNDLQETTY---LYIPNNAVGAIIGTRGSHIRSIMRFSNA 399
            .:....|....|...:.....||  .||...|.:   |..|...:.::||..|:.|..:.:.:.|
plant   253 LAPLMGSYGRDAGDWSRPLYQPP--RNDPPATEFFIRLVSPVENIASVIGKGGALINQLRQETRA 315

  Fly   400 SLKIAPLDADKPLDQQTERKVTIVG----------TPEGQWKAQYMIFEKM-REEGFMCGTDDVR 453
            ::|:     |....:..:..:||..          |.|...:.|....:|: |:.|.      |.
plant   316 TIKV-----DSSRTEGNDCLITISAREVFEDAYSPTIEAVMRLQPKCSDKVERDSGL------VS 369

  Fly   454 LTVELLVASSQVGRIIGKGGQNVRELQRVTGSVIKLPEHALAPPSGGDEETPVHIIGLFYSVQSA 518
            .|..|||.||::|.|:||||..:.|::|:|.:.|::......|....|::..|.|.|
plant   370 FTTRLLVPSSRIGCILGKGGAIITEMRRMTKANIRILGKENLPKVASDDDEMVQISG-------- 426

  Fly   519 QRRIRAMMLSTNPPPITKKQKAAKEQLQQQQQSL-------AGAASSGSQQQQPQSPSQQQALPP 576
                              :...|||.|.|....|       .||.|               ||.|
plant   427 ------------------ELDVAKEALIQITSRLRANVFDREGAVS---------------ALMP 458

  Fly   577 QLHHQPVSSASSSSTPPAHHQQQASTAATSHQLQQQQPSPPPPGNATAAA 626
            .|.:.||:        |....:....:..|.:|::..|.|...|::..:|
plant   459 VLPYVPVA--------PDAGDRFDYDSRDSRRLERGNPYPGGYGSSGVSA 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Imp	NP_001245616.1	RRM	<37..>146	CDD:223796	7/48 (15%)
		RRM2_VICKZ	42..118	CDD:240805	0/7 (0%)
		KH-I	145..208	CDD:238053	19/66 (29%)
		KH-I	232..296	CDD:238053	16/67 (24%)
		KH-I	369..436	CDD:238053	15/79 (19%)
		KH-I	455..522	CDD:238053	21/66 (32%)
AT5G15270	NP_197031.3	KH-I_PEPPER_rpt1_like	49..124	CDD:411887	22/77 (29%)
		KH-I_PEPPER_rpt2_like	148..219	CDD:411888	18/72 (25%)
		KH-I_PEPPER_rpt1_like	283..351	CDD:411887	13/72 (18%)
		KH-I_PEPPER_rpt2_like	371..443	CDD:411888	26/97 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D286875at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3056
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920