Protein Alignment Imp and Nova1

DIOPT Version :9

• Sequence 1: NP_001245616.1
• Gene: Imp / 32009
• FlyBaseID: FBgn0285926
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_036013454.1
• Gene: Nova1 / 664883
• MGIID: 104297
• Length: 530
• Species: Mus musculus
• Alignment Length: 531
• Identity: 119/531 - (22%)
• Similarity: 189/531 - (35%)
• Gaps: 169/531 - (31%)

  Fly   116 LDKNQRRSQRNQRNPYPG---MPGPGRQADFPLRILVQSEMVGAIIGRQGSTIRTITQQSRARVD 177
            ||....|.:..:..|..|   ....|....:.|::|:.|...|:|||:.|.||..:.:::.|.:.
Mouse    20 LDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIK 84

  Fly   178 VHRKENV--GSLEKSITIYGNPENCTNA-----CKRILEVMQQEAISTNKGELSPECS------- 228
            :.:.::.  |:.|:...|.|..| ..||     .::|.|:.|..|.:.....|.|:.:
Mouse    85 LSKSKDFYPGTTERVCLIQGTIE-ALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIK 148

  Fly   229 ---------------------------------------------EICLKILAHNNLIGRIIGKS 248
                                                         :|.:||:..|:..|.||||.
Mouse   149 QTLPSSPTTTKSSPSDPMTTSRANQVQYHPLIYTILSQRLCQLEKQILVKIIVPNSTAGLIIGKG 213

  Fly   249 GNTIKRIMQDTDTKITVSSINDINSFNL-ERIITVKGLIENMSRAENQISTKLRQSYENDLQAMA 312
            |.|:|.||:.:...:.:|...|  ..|| ||::||.|..|...:|...|..|:::    |.|:.:
Mouse   214 GATVKAIMEQSGAWVQLSQKPD--GINLQERVVTVSGEPEQNRKAVELIIQKIQE----DPQSGS 272

  Fly   313 PQSLMFPGLHPMAMMSTPGNGMVFNTSMPFPSCQSFA----------MSKTPASVVPPVFPNDLQ 367
            ..::.:..:......|.|......||:...|:..:.|          ::..|| |:.....|||.
Mouse   273 CLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPA-VLSGFTGNDLV 336

  Fly   368 ETT--------YLYIPNN---------AVGAII-------------------------------G 384
            ..|        |.|..|.         |.||:.                               |
Mouse   337 AITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGG 401

  Fly   385 TRGSHIRSIMRFSNASLKIAP------LDADKPLDQQTERKVTIVGTPEGQWKAQYMIFEKMREE 443
            |.|:       |:..||..|.      ..|..||...     .|:||            ||..:
Mouse   402 TAGT-------FALGSLAAATAATNGYFGAASPLAAS-----AILGT------------EKSTD- 441

  Fly   444 GFMCGTDDVRLTVELLVASSQVGRIIGKGGQNVRELQRVTGSVIKLPEHALAPPSGGDEETPVHI 508
                |:.||   ||:.|..:.||.|:||||:.:.|.|.:||:.|::.:.....|  |.....|.|
Mouse   442 ----GSKDV---VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVP--GTRNRKVTI 497

  Fly   509 IGLFYSVQSAQ 519
            .|...:.|:||
Mouse   498 TGTPAATQAAQ 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Imp	NP_001245616.1	RRM	<37..>146	CDD:223796	6/32 (19%)
		RRM2_VICKZ	42..118	CDD:240805	1/1 (100%)
		KH-I	145..208	CDD:238053	18/69 (26%)
		KH-I	232..296	CDD:238053	24/64 (38%)
		KH-I	369..436	CDD:238053	20/120 (17%)
		KH-I	455..522	CDD:238053	23/65 (35%)
Nova1	XP_036013454.1	KH-I_NOVA_rpt1	49..121	CDD:411863	18/72 (25%)
		KH-I_NOVA_rpt2	197..264	CDD:411864	25/68 (37%)
		KH-I_NOVA_rpt3	445..515	CDD:411807	25/69 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831602
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840