Protein Alignment Imp and Pcbp4

DIOPT Version :10

• Sequence 1: NP_001245616.1
• Gene: Imp / 32009
• FlyBaseID: FBgn0285926
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_067542.3
• Gene: Pcbp4 / 59092
• MGIID: 1890471
• Length: 403
• Species: Mus musculus
• Alignment Length: 450
• Identity: 112/450 - (24%)
• Similarity: 184/450 - (40%)
• Gaps: 91/450 - (20%)

  Fly   136 GPGRQADFPLRILVQSEMVGAIIGRQGSTIRTITQQSRARVDVHRKENVGSL-EKSITIYGNPEN 199
            ||.......||:|:..:.||:|||::|.|::.|.:||.||:.:    :.||. |:..||.|:...
Mouse    11 GPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI----SEGSCPERITTITGSTAA 71

  Fly   200 CTNACKRILEVMQQE--AISTNKGELSPECSEICLKILAHNNLIGRIIGKSGNTIKRIMQDTDTK 262
            ..:|...|...:.::  |...|.|.:|.  ..:.|:::...:..|.:|||:|..||.|.:.|..:
Mouse    72 VFHAVSMIAFKLDEDLCAAPANGGSVSR--PPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQ 134

  Fly   263 ITVSSINDINSFNLERIITVKGLIENMSRAENQISTKLRQSYENDLQAMAPQSLMFPGLHPMAMM 327
            :.|:  .|:...:.||.:||.|:.:.:.....||...:.:|        .|:....| .||...:
Mouse   135 VQVA--GDLLPNSTERAVTVSGVPDAIILCVRQICAVILES--------PPKGATIP-YHPSLSL 188

  Fly   328 STPGNGMVFNTSMPFPSCQSFAMSKTPA------------------SVVPPVFPNDLQETTYLYI 374
            .|    ::.:.:..| |.|....:.|||                  ||||.:.|:....:....:
Mouse   189 GT----VLLSANQGF-SVQGQYGAVTPAEVTKLQQLSGHAVPFASPSVVPGLDPSTQTSSQEFLV 248

  Fly   375 PNNAVGAIIGTRGSHIRSIMRFSNASLKIAPLDADKPLDQQTERKVTIVGTPEGQWKAQYMIFEK 439
            ||:.:|.:||.:||.|..|.:.|.|.:||.     ...:...||.|||.|:|.....|||:|
Mouse   249 PNDLIGCVIGRQGSKISEIRQMSGAHIKIG-----NQAEGAGERHVTITGSPVSIALAQYLI--- 305

  Fly   440 MREEGFMCGTDDVRLTVELLVASSQVGRIIGKGGQNVRELQRVTGSVIKLPEHALAPPSGGDEET 504
                           |..|..|.|..|...|....:             ||. ..:||.......
Mouse   306 ---------------TACLETAKSTSGGTPGSAPAD-------------LPT-PFSPPLTALPTA 341

  Fly   505 PVHIIGLFYSVQSAQ----RRIRAMML---STNPPP----ITKKQKAAKEQLQQQQQSLA 553
            |..::|..|::..:.    :.:..:.|   |..|||    .|.|..||....:.::|..:
Mouse   342 PPGLLGTPYAISLSNFIGLKPVPFLALPPASPGPPPGLAAYTAKMAAANGSKKAERQKFS 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Imp	NP_001245616.1	RRM2_VICKZ	42..118	CDD:409794
		KH-I_IGF2BP_rpt1	144..211	CDD:411828	23/67 (34%)
		KH-I_IGF2BP_rpt2	231..302	CDD:411829	19/70 (27%)
		KH-I_IGF2BP_rpt3	368..437	CDD:411830	23/68 (34%)
		KH-I_IGF2BP_rpt4	455..523	CDD:411831	13/71 (18%)
Pcbp4	NP_067542.3	KH-I_PCBP4_rpt1	17..86	CDD:411945	23/72 (32%)
		KH-I_PCBP4_rpt2	101..172	CDD:411948	19/72 (26%)
		KH-I_PCBP4_rpt3	241..308	CDD:411951	25/89 (28%)