Protein Alignment Imp and Fubp3

DIOPT Version :9

• Sequence 1: NP_001245616.1
• Gene: Imp / 32009
• FlyBaseID: FBgn0285926
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_001028561.2
• Gene: Fubp3 / 320267
• MGIID: 2443699
• Length: 575
• Species: Mus musculus
• Alignment Length: 645
• Identity: 127/645 - (19%)
• Similarity: 220/645 - (34%)
• Gaps: 196/645 - (30%)

  Fly    93 QAQRAAVGLNGVEFEGSKLHAEQL-DKNQRRSQRNQRNPY--PGMPGPG---------------- 138
            |.|.|.||:....|..:.....|: .|.......|...|.  |.:.|.|
Mouse     6 QGQSAPVGMKAEGFVDALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRALDDGVGNQLGA 70

  Fly   139 ---RQADFPLRILVQSEMVGAIIGRQGSTIRTITQQSRARVDVHRKENVGSLEKSITIYGNPENC 200
               ::|.......|..:|||.||||.|..|..|..:|..::.: ..|:.|..|:...:.|.||:.
Mouse    71 LVHQRAVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQI-ASESSGIPERPCVLTGTPESI 134

  Fly   201 TNACKRILEVMQQEAISTNKGELSPEC------------SEICLKILAHNNLIGRIIGKSGNTIK 253
            ..| ||:|            |::...|            :....::|...:.:|.:|||.|.|||
Mouse   135 EQA-KRLL------------GQIVDRCRNGPGFHNDMDGNSTIQELLIPASKVGLVIGKGGETIK 186

  Fly   254 RIMQDTDTKITVSSINDINSFNLERIITVKGLIENMSRAENQISTKLRQSYENDLQAMAPQSLMF 318
            ::.:.|..|:.:.....:.: ..::.:.:.|....:.:|...:...:|:..:.|.:.:...
Mouse   187 QLQERTGVKMVMIQDGPLPT-GADKPLRITGDPFKVQQAREMVLEIIREKDQADFRGVRSD---- 246

  Fly   319 PGLHPMAMMSTPGNGMVFNTSMPFPSCQSFAMSKTPASVVPPVFPNDLQETTYLYIPNNAVGAII 383
                   ..|..|.|.:                                   .:.:|...||.:|
Mouse   247 -------FTSRAGGGSI-----------------------------------EVSVPRFVVGIVI 269

  Fly   384 GTRGSHIRSIMRFSNASLKIAPLDADKPLDQQTERKVTIVGTPEGQWKAQYMIFE-----KMRE- 442
            |..|..|:.|...:...::..|.|...|     ||...::|.|:....|..:|.|     :.||
Mouse   270 GRNGEMIKKIQNDAGVRIQFKPDDGISP-----ERAAQVMGPPDRCQHAARIINELILTAQEREI 329

  Fly   443 --------------EGFMCGTDDVRLTVELLVASSQVGRIIGKGGQNVRELQRVTGSVIKLPEHA 493
                          ..:..||......:...|.:.:.|.:|||||:|::.:.:.:|:.::|..:
Mouse   330 LGGLTVTRGRGRGRSDWSVGTPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRN- 393

  Fly   494 LAPPSGGDEETPVHII-GLFYSVQSAQRRIR---------------------------------- 523
              ||...|....:..| |....::.|:..|.
Mouse   394 --PPPNTDPNLRIFTIRGAPQQMEVARHLIDEKVGGASLGAPAAFGQSPFSQPPAAPHQNTFPPR 456

  Fly   524 -----AMMLSTNP-------PP--ITKKQKAAKEQLQQQQQSLAGAASSGSQQQQPQS--PSQQQ 572
                 |..::.||       ||  :|:...:..:..||..|.:.      |||.|||:  |...:
Mouse   457 GFPNIAAKVNGNPHSTPVSGPPAFLTQGWGSTYQAWQQPTQQVP------SQQSQPQNSQPDYSK 515

  Fly   573 ALPPQLHHQ--PVSSASSSSTPP-------AHHQQQAS-------TAATSHQLQQQQPSP 616
            |.......|  |.|:|..:|:||       .:::|||:       .|....|:..|.|:|
Mouse   516 AWEDYYKKQSHPTSAAPQASSPPDYTMAWAEYYRQQAAFYGQTLGQAQAHSQVCSQSPAP 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Imp	NP_001245616.1	RRM	<37..>146	CDD:223796	14/74 (19%)
		RRM2_VICKZ	42..118	CDD:240805	7/25 (28%)
		KH-I	145..208	CDD:238053	21/62 (34%)
		KH-I	232..296	CDD:238053	13/63 (21%)
		KH-I	369..436	CDD:238053	16/66 (24%)
		KH-I	455..522	CDD:238053	16/67 (24%)
Fubp3	NP_001028561.2	KH-I	79..141	CDD:238053	21/63 (33%)
		KH_1	165..230	CDD:365809	13/65 (20%)
		KH-I	255..317	CDD:238053	16/101 (16%)
		KH_1	357..423	CDD:365809	17/68 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831608
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840