Protein Alignment Imp and Nova1

DIOPT Version :10

• Sequence 1: NP_001245616.1
• Gene: Imp / 32009
• FlyBaseID: FBgn0285926
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_001401845.1
• Gene: Nova1 / 298992
• RGDID: 621345
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 508
• Identity: 114/508 - (22%)
• Similarity: 184/508 - (36%)
• Gaps: 146/508 - (28%)

  Fly   116 LDKNQRRSQRNQRNPYPG---MPGPGRQADFPLRILVQSEMVGAIIGRQGSTIRTITQQSRARVD 177
            ||....|.:..:..|..|   ....|....:.|::|:.|...|:|||:.|.||..:.:::.|.:.
  Rat    20 LDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIK 84

  Fly   178 VHRKENV------------GSLEKSITIYG----------------------NPENCTNACKRIL 208
            :.:.::.            |::|....::|                      .|:...|. .||.
  Rat    85 LSKSKDFYPGTTERVCLIQGTIEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNP-DRIK 148

  Fly   209 EVMQQEAISTNKGELSPECSEIC--LKILAHNNLIGRIIGKSGNTIKRIMQDTDTKITVSSINDI 271
            :.:.....:|......|..:...  :||:..|:..|.||||.|.|:|.||:.:...:.:|...|
  Rat   149 QTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQKPD- 212

  Fly   272 NSFNL-ERIITVKGLIENMSRAENQISTKLRQSYENDLQAMAPQSLMFPGLHPMAMMSTPGNGMV 335
             ..|| ||::||.|..|...:|...|..|:::    |.|:.:..::.:..:......|.|.....
  Rat   213 -GINLQERVVTVSGEPEQNRKAVELIIQKIQE----DPQSGSCLNISYANVTGPVANSNPTGSPY 272

  Fly   336 FNTSMPFPSCQSFA----------MSKTPASVVPPVFPNDLQETT--------YLYIPNN----- 377
            .||:...|:..:.|          ::..|| |:.....|||...|        |.|..|.
  Rat   273 ANTAEVLPTAAAAAGLLGHANLAGVAAFPA-VLSGFTGNDLVAITSALNTLASYGYNLNTLGLGL 336

  Fly   378 ----AVGAII-------------------------------GTRGSHIRSIMRFSNASLKIAP-- 405
                |.||:.                               ||.|:       |:..||..|.
  Rat   337 SQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGT-------FALGSLAAATAA 394

  Fly   406 ----LDADKPLDQQTERKVTIVGTPEGQWKAQYMIFEKMREEGFMCGTDDVRLTVELLVASSQVG 466
                ..|..||...     .|:||            ||..:     |:.||   ||:.|..:.||
  Rat   395 TNGYFGAASPLAAS-----AILGT------------EKSTD-----GSKDV---VEIAVPENLVG 434

  Fly   467 RIIGKGGQNVRELQRVTGSVIKLPEHALAPPSGGDEETPVHIIGLFYSVQSAQ 519
            .|:||||:.:.|.|.:||:.|::.:.....|  |.....|.|.|...:.|:||
  Rat   435 AILGKGGKTLVEYQELTGARIQISKKGEFVP--GTRNRKVTITGTPAATQAAQ 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Imp	NP_001245616.1	RRM2_VICKZ	42..118	CDD:409794	1/1 (100%)
		KH-I_IGF2BP_rpt1	144..211	CDD:411828	18/100 (18%)
		KH-I_IGF2BP_rpt2	231..302	CDD:411829	26/73 (36%)
		KH-I_IGF2BP_rpt3	368..437	CDD:411830	20/122 (16%)
		KH-I_IGF2BP_rpt4	455..523	CDD:411831	23/65 (35%)
Nova1	NP_001401845.1	KH-I_NOVA_rpt1	49..121	CDD:411863	14/71 (20%)
		KH-I_NOVA_rpt2	172..241	CDD:411864	25/70 (36%)
		KH-I_NOVA_rpt3	422..492	CDD:411807	25/69 (36%)