DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ant2 and SLC25A31

DIOPT Version :9

Sequence 1:NP_001259432.1 Gene:Ant2 / 32008 FlyBaseID:FBgn0025111 Length:307 Species:Drosophila melanogaster
Sequence 2:NP_112581.1 Gene:SLC25A31 / 83447 HGNCID:25319 Length:315 Species:Homo sapiens


Alignment Length:295 Identity:204/295 - (69%)
Similarity:240/295 - (81%) Gaps:3/295 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 DLKSFLMDFMMGGVSAAIAKTAVAPIERVKLILQVQEVSKQIAADQRYKGIVDCFIRIPKEQGFS 78
            |..||..|.:.|||:||::||||||||||||:||||..||||:.:.||||:|||.:|||:||||.
Human    16 DASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFF 80

  Fly    79 SFWRGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASGGAAGATSLCFVYP 143
            |||||||||||||||||||||||||.||.:|:.||:|.|||||.|..||||||||||||||.|||
Human    81 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYP 145

  Fly   144 LDFARTRLAADVGKG-GNREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTC 207
            ||||||||..|:||| ..|:|.||.||:||:.||||..|||:||.||||||::|||:|||.|||.
Human   146 LDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTV 210

  Fly   208 RDFLPNPKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMVYKNTAHCWLVIAK 272
            :..||.||.|||.||:.|||||||.:||.||||||||||||||||..|.:  ||.|..|::.|.:
Human   211 KGLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAKRQ--YKGTLDCFVKIYQ 273

  Fly   273 QEGIGAFFKGALSNIIRGTGGALVLALYDEMKKYF 307
            .|||.:||:||.||::|||||||||.|||::|::|
Human   274 HEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEFF 308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ant2NP_001259432.1 PTZ00169 15..305 CDD:240302 201/290 (69%)
Mito_carr 17..111 CDD:278578 70/93 (75%)
Mito_carr 119..215 CDD:278578 67/96 (70%)
Mito_carr 218..307 CDD:278578 57/88 (65%)
SLC25A31NP_112581.1 Solcar 1 18..110 69/91 (76%)
PTZ00169 19..309 CDD:240302 203/292 (70%)
Solcar 2 123..213 63/89 (71%)
Solcar 3 220..307 58/88 (66%)
Important for transport activity. /evidence=ECO:0000250|UniProtKB:P12235 247..252 4/4 (100%)
Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722 247..252 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165158767
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0749
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG54049
OrthoDB 1 1.010 - - D440386at33208
OrthoFinder 1 1.000 - - FOG0000386
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100505
Panther 1 1.100 - - O PTHR45635
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R28
SonicParanoid 1 1.000 - - X286
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1110.750

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