DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ant2 and SLC25A23

DIOPT Version :10

Sequence 1:NP_511110.1 Gene:Ant2 / 32008 FlyBaseID:FBgn0025111 Length:307 Species:Drosophila melanogaster
Sequence 2:XP_011526576.1 Gene:SLC25A23 / 79085 HGNCID:19375 Length:624 Species:Homo sapiens


Alignment Length:289 Identity:79/289 - (27%)
Similarity:140/289 - (48%) Gaps:27/289 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 GGVSAAIAKTAVAPIERVKLILQVQEVSKQIAADQRYKGIVDCFIRIPKEQGFSSFWRGNLANVI 89
            |.|:.|:::|..||::|:|:.:||.      |:......|:.....:..|.|..|.||||..||:
Human   239 GAVAGAVSRTGTAPLDRLKVFMQVH------ASKTNRLNILGGLRSMVLEGGIRSLWRGNGINVL 297

  Fly    90 RYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASGGAAGATSLCFVYPLDFARTRLAAD 154
            :..|..|:.|...:..|...||     :|...|......:|..||||:...:||::..:|||.  
Human   298 KIAPESAIKFMAYEQIKRAILG-----QQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLT-- 355

  Fly   155 VGKGGNREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCRDF----LPNPK 215
            :.:.|  ::.||:||..::::.:||...|||::.:|.||:.|.......|:|.:::    ..:..
Human   356 LRRTG--QYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDS 418

  Fly   216 STP-FYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMVYKNTAHCWLV--IAKQEGIG 277
            :.| ..|..|...:.:|...|||||...||.||..|:.::....:    :...|:  |..|||:.
Human   419 ADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQL----SMLGLLRHILSQEGMR 479

  Fly   278 AFFKGALSNIIRGTGG-ALVLALYDEMKK 305
            ..::|...|.::.... ::...:|:.||:
Human   480 GLYRGIAPNFMKVIPAVSISYVVYENMKQ 508

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ant2NP_511110.1 PTZ00169 15..305 CDD:240302 78/287 (27%)
SLC25A23XP_011526576.1 FRQ1 8..142 CDD:444056
PTZ00169 237..510 CDD:240302 79/289 (27%)
Blue background indicates that the domain is not in the aligned region.

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