DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ant2 and sea

DIOPT Version :9

Sequence 1:NP_001259432.1 Gene:Ant2 / 32008 FlyBaseID:FBgn0025111 Length:307 Species:Drosophila melanogaster
Sequence 2:NP_001027175.1 Gene:sea / 3772221 FlyBaseID:FBgn0037912 Length:317 Species:Drosophila melanogaster


Alignment Length:317 Identity:92/317 - (29%)
Similarity:135/317 - (42%) Gaps:38/317 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 EGGGGGHGKGDLKSFLMDFMMGGVSAAIAKTAVAPIERVKLILQVQEVSKQIAADQRYKGIVDCF 68
            |.|......|.:.  |...:.||::..|......|.|.||..||:.|.    .|.::|.||.||.
  Fly    21 EHGAAAADSGQVG--LKGIVAGGITGGIEICITYPTEYVKTQLQLDEK----GAAKKYNGIFDCV 79

  Fly    69 IRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASG-GA 132
            .:...|:||...:||....|....|..|..|...:..||   ..||...|...  :|.|..| ||
  Fly    80 KKTVGERGFLGLYRGLSVLVYGSIPKSAARFGAFEFLKS---NAVDSRGQLSN--SGKLLCGLGA 139

  Fly   133 AGATSLCFVYPLDFARTRLAADVGKGGNREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYR 197
            ....::..|.|::..:.:...| .:.||.:|.|....:.::|||:|..|:|:|...::......:
  Fly   140 GVCEAIVAVTPMETIKVKFIND-QRSGNPKFRGFAHGVGQIIKSEGISGIYKGLTPTILKQGSNQ 203

  Fly   198 AAYFGFYDTCRDFL-------PNPKSTPFYVSWAIAQVVTTVAGIASY----PFDTVRRRMMMQS 251
            |..|...::.:|..       |.||        .:..|...:||.||.    |.|.|:.||   .
  Fly   204 AIRFFVLESLKDLYKGDDHTKPVPK--------LVVGVFGAIAGAASVFGNTPLDVVKTRM---Q 257

  Fly   252 GLKKSEMVYKNTAHCWLVIAKQEGIGAFFKGALSNIIR-GTGGALVLALYDEMKKYF 307
            ||:.|:  |||||||.:.|.|.||..||:||.:..:.| ....|:...:||.....|
  Fly   258 GLEASK--YKNTAHCAVEILKNEGPAAFYKGTVPRLGRVCLDVAITFMIYDSFMDLF 312

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ant2NP_001259432.1 PTZ00169 15..305 CDD:240302 88/302 (29%)
Mito_carr 17..111 CDD:278578 28/93 (30%)
Mito_carr 119..215 CDD:278578 23/103 (22%)
Mito_carr 218..307 CDD:278578 32/93 (34%)
seaNP_001027175.1 PTZ00168 34..302 CDD:185494 86/290 (30%)
Mito_carr 34..117 CDD:278578 26/86 (30%)
Mito_carr 125..220 CDD:278578 23/97 (24%)
Mito_carr 235..314 CDD:278578 32/83 (39%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45442076
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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