Protein Alignment Ant2 and SLC25A24

DIOPT Version :10

• Sequence 1: NP_511110.1
• Gene: Ant2 / 32008
• FlyBaseID: FBgn0025111
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_037518.3
• Gene: SLC25A24 / 29957
• HGNCID: 20662
• Length: 477
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 85/291 - (29%)
• Similarity: 147/291 - (50%)
• Gaps: 27/291 - (9%)

  Fly    23 MMGGVSAAIAKTAVAPIERVKLILQVQEVSKQIAADQRYKGIVDCFIRIPKEQGFSSFWRGNLAN 87
            :.||::.|:::|:.||::|:|:::||.      .:......|...|.::.||.|..|.||||..|
Human   199 LAGGIAGAVSRTSTAPLDRLKIMMQVH------GSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTN 257

  Fly    88 VIRYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASGGAAGATSLCFVYPLDFARTRLA 152
            ||:..|..|:.|...:.||.:......|...|.|..:|::     ||||:..|:||::..:||||
Human   258 VIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM-----AGATAQTFIYPMEVMKTRLA 317

  Fly   153 ADVGKGGNREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCR-----DFLP 212
              |||.|  :::|:.||..|::|.:|....|:|::.::.||:.|.......|:..:     :|..
Human   318 --VGKTG--QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAK 378

  Fly   213 NPKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMVYKNTAHCWLVIAKQEGIG 277
            :..:....|......:.:|...:||||...||.||..|:.|:.|..:  |....:..|..:|||.
Human   379 DSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQL--NMVGLFRRIISKEGIP 441

  Fly   278 AFFKGALSN---IIRGTGGALVLALYDEMKK 305
            ..::|...|   ::...|.:.|  :|:.||:
Human   442 GLYRGITPNFMKVLPAVGISYV--VYENMKQ 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ant2	NP_511110.1	PTZ00169	15..305	CDD:240302	84/289 (29%)
SLC25A24	NP_037518.3	Regulatory N-terminal domain. /evidence=ECO:0000269|PubMed:24332718, ECO:0000269|PubMed:26164100	1..173
		FRQ1	18..151	CDD:444056
		Linker region. /evidence=ECO:0000269|PubMed:24332718	159..168
		C-terminal transmembrane transporter domain. /evidence=ECO:0000269|PubMed:24332718	174..477		85/291 (29%)
		PTZ00169	199..472	CDD:240302	85/291 (29%)