Protein Alignment Ant2 and SLC25A6

DIOPT Version :10

• Sequence 1: NP_511110.1
• Gene: Ant2 / 32008
• FlyBaseID: FBgn0025111
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_001627.2
• Gene: SLC25A6 / 293
• HGNCID: 10992
• Length: 298
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 217/290 - (74%)
• Similarity: 243/290 - (83%)
• Gaps: 1/290 - (0%)

  Fly    17 SFLMDFMMGGVSAAIAKTAVAPIERVKLILQVQEVSKQIAADQRYKGIVDCFIRIPKEQGFSSFW 81
            ||..||:.||::|||:||||||||||||:||||..|||||||::|||||||.:|||||||..|||
Human     7 SFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFW 71

  Fly    82 RGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASGGAAGATSLCFVYPLDF 146
            ||||||||||||||||||||||.||.:||||||||.||||:||||||||||||||||||||||||
Human    72 RGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLCFVYPLDF 136

  Fly   147 ARTRLAADVGKGG-NREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCRDF 210
            |||||||||||.| .|||.||.|||:|:.||||..|||:||.||||||:||||||||.|||.:..
Human   137 ARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRAAYFGVYDTAKGM 201

  Fly   211 LPNPKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMVYKNTAHCWLVIAKQEG 275
            ||:||:|...|||.|||.||.|||:.||||||||||||||||.|.::::|..|..||..|.:.||
Human   202 LPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIFRDEG 266

  Fly   276 IGAFFKGALSNIIRGTGGALVLALYDEMKK 305
            ..||||||.||::||.|||.||.||||:||
Human   267 GKAFFKGAWSNVLRGMGGAFVLVLYDELKK 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ant2	NP_511110.1	PTZ00169	15..305	CDD:240302	215/288 (75%)
SLC25A6	NP_001627.2	PTZ00169	3..298	CDD:240302	217/290 (75%)
		Solcar 1	6..98		73/90 (81%)
		Solcar 2	111..201		72/89 (81%)
		Solcar 3	212..297		56/85 (66%)
		Important for transport activity. /evidence=ECO:0000250|UniProtKB:P12235	235..240		4/4 (100%)
		Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722	235..240		4/4 (100%)