DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ant2 and SLC25A5

DIOPT Version :9

Sequence 1:NP_001259432.1 Gene:Ant2 / 32008 FlyBaseID:FBgn0025111 Length:307 Species:Drosophila melanogaster
Sequence 2:NP_001143.2 Gene:SLC25A5 / 292 HGNCID:10991 Length:298 Species:Homo sapiens


Alignment Length:291 Identity:215/291 - (73%)
Similarity:242/291 - (83%) Gaps:1/291 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 SFLMDFMMGGVSAAIAKTAVAPIERVKLILQVQEVSKQIAADQRYKGIVDCFIRIPKEQGFSSFW 81
            ||..||:.|||:|||:||||||||||||:||||..||||.||::||||:||.:|||||||..|||
Human     7 SFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71

  Fly    82 RGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASGGAAGATSLCFVYPLDF 146
            ||||||||||||||||||||||.||.:|||||||..|||.:||||||||||||||||||||||||
Human    72 RGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCFVYPLDF 136

  Fly   147 ARTRLAADVGK-GGNREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCRDF 210
            ||||||||||| |..|||.||.|||:|:.||||..|||:||.||||||:||||||||.|||.:..
Human   137 ARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGM 201

  Fly   211 LPNPKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMVYKNTAHCWLVIAKQEG 275
            ||:||:|...:||.|||.||.|||:.||||||||||||||||.|.::::|..|..||..||:.||
Human   202 LPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEG 266

  Fly   276 IGAFFKGALSNIIRGTGGALVLALYDEMKKY 306
            ..||||||.||::||.|||.||.||||:|||
Human   267 GKAFFKGAWSNVLRGMGGAFVLVLYDEIKKY 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ant2NP_001259432.1 PTZ00169 15..305 CDD:240302 212/288 (74%)
Mito_carr 17..111 CDD:278578 73/93 (78%)
Mito_carr 119..215 CDD:278578 75/96 (78%)
Mito_carr 218..307 CDD:278578 57/89 (64%)
SLC25A5NP_001143.2 Mito_carr 6..101 CDD:278578 73/93 (78%)
Solcar 1 6..98 72/90 (80%)
PTZ00169 7..296 CDD:240302 212/288 (74%)
Mito_carr 109..206 CDD:278578 75/96 (78%)
Solcar 2 111..201 71/89 (80%)
Mito_carr 209..297 CDD:278578 55/87 (63%)
Solcar 3 212..297 55/84 (65%)
Important for transport activity. /evidence=ECO:0000250|UniProtKB:P12235 235..240 4/4 (100%)
Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722 235..240 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 135 1.000 Domainoid score I4973
eggNOG 1 0.900 - - E1_KOG0749
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG54049
OrthoDB 1 1.010 - - D440386at33208
OrthoFinder 1 1.000 - - FOG0000386
OrthoInspector 1 1.000 - - mtm8481
orthoMCL 1 0.900 - - OOG6_100505
Panther 1 1.100 - - O PTHR45635
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R28
SonicParanoid 1 1.000 - - X286
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
1211.860

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