Protein Alignment Ant2 and SLC25A5

DIOPT Version :10

• Sequence 1: NP_511110.1
• Gene: Ant2 / 32008
• FlyBaseID: FBgn0025111
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_001143.2
• Gene: SLC25A5 / 292
• HGNCID: 10991
• Length: 298
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 215/291 - (73%)
• Similarity: 242/291 - (83%)
• Gaps: 1/291 - (0%)

  Fly    17 SFLMDFMMGGVSAAIAKTAVAPIERVKLILQVQEVSKQIAADQRYKGIVDCFIRIPKEQGFSSFW 81
            ||..||:.|||:|||:||||||||||||:||||..||||.||::||||:||.:|||||||..|||
Human     7 SFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71

  Fly    82 RGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASGGAAGATSLCFVYPLDF 146
            ||||||||||||||||||||||.||.:|||||||..|||.:||||||||||||||||||||||||
Human    72 RGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCFVYPLDF 136

  Fly   147 ARTRLAADVGK-GGNREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCRDF 210
            ||||||||||| |..|||.||.|||:|:.||||..|||:||.||||||:||||||||.|||.:..
Human   137 ARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGM 201

  Fly   211 LPNPKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMVYKNTAHCWLVIAKQEG 275
            ||:||:|...:||.|||.||.|||:.||||||||||||||||.|.::::|..|..||..||:.||
Human   202 LPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEG 266

  Fly   276 IGAFFKGALSNIIRGTGGALVLALYDEMKKY 306
            ..||||||.||::||.|||.||.||||:|||
Human   267 GKAFFKGAWSNVLRGMGGAFVLVLYDEIKKY 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ant2	NP_511110.1	PTZ00169	15..305	CDD:240302	212/288 (74%)
SLC25A5	NP_001143.2	Solcar 1	6..98		72/90 (80%)
		PTZ00169	7..296	CDD:240302	212/288 (74%)
		Solcar 2	111..201		71/89 (80%)
		Solcar 3	212..297		55/84 (65%)
		Important for transport activity. /evidence=ECO:0000250|UniProtKB:P12235	235..240		4/4 (100%)
		Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722	235..240		4/4 (100%)