DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ant2 and ant-1.2

DIOPT Version :9

Sequence 1:	NP_001259432.1	Gene:	Ant2 / 32008	FlyBaseID:	FBgn0025111	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_491927.1	Gene:	ant-1.2 / 189112	WormBaseID:	WBGene00007057	Length:	300	Species:	Caenorhabditis elegans

Alignment Length:	292	Identity:	193/292 - (66%)
Similarity:	236/292 - (80%)	Gaps:	3/292 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 DLKSFLMDFMMGGVSAAIAKTAVAPIERVKLILQVQEVSKQIAADQRYKGIVDCFIRIPKEQGFS 78
            |.:.||:|...||.:|||:||||||||||||:|||.:||:.:.||::||||:|...|:|||||::
Worm     8 DYRKFLVDLASGGTAAAISKTAVAPIERVKLLLQVSDVSETVTADKKYKGIMDVLARVPKEQGYA 72

  Fly    79 SFWRGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASGGAAGATSLCFVYP 143
            :|||||||||:||||||||||||||.||.:|..|:||:|:||:.|||||||||||||||||||||
Worm    73 AFWRGNLANVLRYFPTQALNFAFKDTYKKMFQEGIDKNKEFWKFFAGNLASGGAAGATSLCFVYP 137

  Fly   144 LDFARTRLAADVGKGGNREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCR 208
            |||.||||.||||||.:|||.||.||.:|::||||||||||||.||||||:||||||||.:||.:
Worm   138 LDFVRTRLGADVGKGVDREFQGLTDCFVKIVKSDGPIGLYRGFFVSVQGIIIYRAAYFGMFDTAK 202

  Fly   209 D-FLPNPKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMVYKNTAHCWLVIAK 272
            . :..:.:...|:.:||||||.|..:|..|||:||||||||||||.|  :::||||..|...|.|
Worm   203 TLYSTDGQKLNFFTTWAIAQVGTVGSGYLSYPWDTVRRRMMMQSGRK--DILYKNTLDCVRKIVK 265

  Fly   273 QEGIGAFFKGALSNIIRGTGGALVLALYDEMK 304
            .|||.|.:||.|||:.|.|||||||.:|||::
Worm   266 NEGITALYKGGLSNVFRATGGALVLTIYDEIQ 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ant2	NP_001259432.1	PTZ00169	15..305	CDD:240302	192/291 (66%)
		Mito_carr	17..111	CDD:278578	64/93 (69%)
		Mito_carr	119..215	CDD:278578	72/96 (75%)
		Mito_carr	218..307	CDD:278578	52/87 (60%)
ant-1.2	NP_491927.1	Mito_carr	11..105	CDD:278578	64/93 (69%)
		PTZ00169	12..300	CDD:240302	192/288 (67%)
		Mito_carr	113..209	CDD:278578	72/95 (76%)
		Mito_carr	210..300	CDD:278578	52/90 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	159	1.000	Domainoid score	I2489
eggNOG	1	0.900	-	-		E1_KOG0749
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68194
Inparanoid	1	1.050	421	1.000	Inparanoid score	I1000
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54049
OrthoDB	1	1.010	-	-		D440386at33208
OrthoFinder	1	1.000	-	-		FOG0000386
OrthoInspector	1	1.000	-	-		mtm4814
orthoMCL	1	0.900	-	-		OOG6_100505
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X286
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.740