Protein Alignment Ant2 and Slc25a4

DIOPT Version :10

• Sequence 1: NP_511110.1
• Gene: Ant2 / 32008
• FlyBaseID: FBgn0025111
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_031476.3
• Gene: Slc25a4 / 11739
• MGIID: 1353495
• Length: 298
• Species: Mus musculus
• Alignment Length: 307
• Identity: 221/307 - (71%)
• Similarity: 252/307 - (82%)
• Gaps: 11/307 - (3%)

  Fly     1 MGDEGGGGGHGKGDLKSFLMDFMMGGVSAAIAKTAVAPIERVKLILQVQEVSKQIAADQRYKGIV 65
            |||:.          .|||.||:.||::||::||||||||||||:||||..||||:|:::||||:
Mouse     1 MGDQA----------LSFLKDFLAGGIAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGII 55

  Fly    66 DCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDVYKSVFLGGVDKHKQFWRHFAGNLASG 130
            ||.:||||||||.|||||||||||||||||||||||||.||.:||||||:||||||:||||||||
Mouse    56 DCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASG 120

  Fly   131 GAAGATSLCFVYPLDFARTRLAADVGKGGN-REFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIV 194
            ||||||||||||||||||||||||||||.: ||||||.|||.|:.||||..|||:||.||||||:
Mouse   121 GAAGATSLCFVYPLDFARTRLAADVGKGSSQREFNGLGDCLTKIFKSDGLKGLYQGFSVSVQGII 185

  Fly   195 IYRAAYFGFYDTCRDFLPNPKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMV 259
            ||||||||.|||.:..||:||:....|||.|||.||.|||:.||||||||||||||||.|.::::
Mouse   186 IYRAAYFGVYDTAKGMLPDPKNVHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIM 250

  Fly   260 YKNTAHCWLVIAKQEGIGAFFKGALSNIIRGTGGALVLALYDEMKKY 306
            |..|..||..|||.||..||||||.||::||.|||.||.||||:|||
Mouse   251 YTGTLDCWRKIAKDEGANAFFKGAWSNVLRGMGGAFVLVLYDEIKKY 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ant2	NP_511110.1	PTZ00169	15..305	CDD:240302	215/290 (74%)
Slc25a4	NP_031476.3	PTZ00169	2..298	CDD:240302	220/306 (72%)
		Solcar 1	6..98		71/91 (78%)
		Solcar 2	111..201		73/89 (82%)
		Solcar 3	212..297		57/84 (68%)
		Important for transport activity. /evidence=ECO:0000250|UniProtKB:P12235	235..240		4/4 (100%)
		Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722	235..240		4/4 (100%)