Protein Alignment Ant2 and SLC25A25

DIOPT Version :10

• Sequence 1: NP_511110.1
• Gene: Ant2 / 32008
• FlyBaseID: FBgn0025111
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_001317917.1
• Gene: SLC25A25 / 114789
• HGNCID: 20663
• Length: 515
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 77/294 - (26%)
• Similarity: 148/294 - (50%)
• Gaps: 39/294 - (13%)

  Fly    25 GGVSAAIAKTAVAPIERVKLILQVQEVSKQIAADQRYKGIVDCFIRIPKEQGFSSFWRGNLANVI 89
            ||.:.|:::|..||::|:|:::||.      |:.....|||..|.::.:|.|..|.||||..||:
Human   239 GGGAGAVSRTCTAPLDRLKVLMQVH------ASRSNNMGIVGGFTQMIREGGARSLWRGNGINVL 297

  Fly    90 RYFPTQALNF-AFKDVYKSVFLGGVDK-----HKQFWRHFAGNLASGGAAGATSLCFVYPLDFAR 148
            :..|..|:.| |::.:.:.|   |.|:     |::        |.:|..|||.:...:||::..:
Human   298 KIAPESAIKFMAYEQIKRLV---GSDQETLRIHER--------LVAGSLAGAIAQSSIYPMEVLK 351

  Fly   149 TRLAADVGKGGNREFNGLIDCLMKVIKSDGPIGLYRGFIVSVQGIVIYRAAYFGFYDTCRD---- 209
            ||:|  :.|.|  :::|::||..:::..:|....|:|::.::.||:.|.......|:|.::
Human   352 TRMA--LRKTG--QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQ 412

  Fly   210 -FLPNPKSTPFYVSWAIAQVVTTVAGIASYPFDTVRRRMMMQSGLKKSEMVYKNT--AHCWLVIA 271
             :..|......:|..|...:.:|...:||||...||.||..|:.::.:..|..::  .|    |.
Human   413 HYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKH----IL 473

  Fly   272 KQEGIGAFFKGALSNIIRGTGG-ALVLALYDEMK 304
            :.||....::|...|.::.... ::...:|:.:|
Human   474 RTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ant2	NP_511110.1	PTZ00169	15..305	CDD:240302	77/294 (26%)
SLC25A25	NP_001317917.1	FRQ1	49..189	CDD:444056
		PTZ00169	237..491	CDD:240302	75/276 (27%)