DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sesB and AAC3

DIOPT Version :9

Sequence 1:	NP_727448.1	Gene:	sesB / 32007	FlyBaseID:	FBgn0003360	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_009642.3	Gene:	AAC3 / 852380	SGDID:	S000000289	Length:	307	Species:	Saccharomyces cerevisiae

Alignment Length:	295	Identity:	160/295 - (54%)
Similarity:	199/295 - (67%)	Gaps:	10/295 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 FVKDFAAGGISAAVSKTAVAPIERVKLLLQVQ-HISKQISPDKQYKGMVDCFIRIPKEQGFSSFW 86
            |..:|..||:|||::|||.:||||||:|:|.| .:.||.:.||:|.|:||||.|..|::|..|||
Yeast    12 FAINFLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKKYSGIVDCFKRTAKQEGLISFW 76

  Fly    87 RGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFWRYFAGNLASGGAAGATSLCFVYPLDF 151
            |||.|||||||||||||||||||.|.:|  |..|...:.::|||||||||||||.||.|||.|||
Yeast    77 RGNTANVIRYFPTQALNFAFKDKIKLMF--GFKKEEGYGKWFAGNLASGGAAGALSLLFVYSLDF 139

  Fly   152 ARTRLAAD---TGKGGQREFTGLGNCLTKIFKSDGIVGLYRGFGVSVQGIIIYRAAYFGFYDTAR 213
            ||||||||   :.|||.|:|.||.:...|..|||||.||||||..||.||::||..|||.:|:.:
Yeast   140 ARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLK 204

  Fly   214 GM-LPDPKNTPIYISWAIAQVVTTVAGIVSYPFDTVRRRMMMQSGRKATEVIYKNTLHCWATIAK 277
            .: |....:.....|:.:..||||.|...|||.|||||||||.||:   .|.|...:.|...|..
Yeast   205 PLVLTGSLDGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSGQ---AVKYNGAIDCLKKIVA 266

  Fly   278 QEGTGAFFKGAFSNILRGTGGAFVLVLYDEIKKVL 312
            .||.|:.|||..:||||...||.|:.:||:::.:|
Yeast   267 SEGVGSLFKGCGANILRSVAGAGVISMYDQLQMIL 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sesB	NP_727448.1	Mito_carr	19..116	CDD:278578	59/93 (63%)
		PTZ00169	23..312	CDD:240302	159/293 (54%)
		Mito_carr	124..220	CDD:278578	59/99 (60%)
		Mito_carr	223..312	CDD:278578	39/88 (44%)
AAC3	NP_009642.3	PTZ00169	6..301	CDD:240302	159/293 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	127	1.000	Domainoid score	I1167
eggNOG	1	0.900	-	-		E1_KOG0749
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	303	1.000	Inparanoid score	I496
Isobase	1	0.950	-	0	Normalized mean entropy	S337
OMA	1	1.010	-	-		QHG54049
OrthoFinder	1	1.000	-	-		FOG0000386
OrthoInspector	1	1.000	-	-		mtm9171
orthoMCL	1	0.900	-	-		OOG6_100505
Panther	1	1.100	-	-	O	PTHR45635
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R28
SonicParanoid	1	1.000	-	-		X286
TreeFam	1	0.960	-	-
	14	13.810