DRSC/TRiP Functional Genomics Resources

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Protein Alignment sesB and SLC25A6

DIOPT Version :9

Sequence 1:NP_727448.1 Gene:sesB / 32007 FlyBaseID:FBgn0003360 Length:312 Species:Drosophila melanogaster
Sequence 2:NP_001627.2 Gene:SLC25A6 / 293 HGNCID:10992 Length:298 Species:Homo sapiens


Alignment Length:294 Identity:237/294 - (80%)
Similarity:260/294 - (88%) Gaps:1/294 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 AVGFVKDFAAGGISAAVSKTAVAPIERVKLLLQVQHISKQISPDKQYKGMVDCFIRIPKEQGFSS 84
            |:.|.|||.||||:||:|||||||||||||||||||.||||:.||||||:|||.:|||||||..|
Human     5 AISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLS 69

  Fly    85 FWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFWRYFAGNLASGGAAGATSLCFVYPL 149
            ||||||||||||||||||||||||||||:|||||||:||||||||||||||||||||||||||||
Human    70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLCFVYPL 134

  Fly   150 DFARTRLAADTGKGG-QREFTGLGNCLTKIFKSDGIVGLYRGFGVSVQGIIIYRAAYFGFYDTAR 213
            ||||||||||.||.| :|||.|||:||.||.|||||.|||:||.|||||||||||||||.||||:
Human   135 DFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRAAYFGVYDTAK 199

  Fly   214 GMLPDPKNTPIYISWAIAQVVTTVAGIVSYPFDTVRRRMMMQSGRKATEVIYKNTLHCWATIAKQ 278
            |||||||||.|.:||.|||.||.|||:|||||||||||||||||||..:::|..|:.||..|.:.
Human   200 GMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIFRD 264

  Fly   279 EGTGAFFKGAFSNILRGTGGAFVLVLYDEIKKVL 312
            ||..||||||:||:|||.|||||||||||:|||:
Human   265 EGGKAFFKGAWSNVLRGMGGAFVLVLYDELKKVI 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sesBNP_727448.1 Mito_carr 19..116 CDD:278578 80/95 (84%)
PTZ00169 23..312 CDD:240302 235/289 (81%)
Mito_carr 124..220 CDD:278578 83/96 (86%)
Mito_carr 223..312 CDD:278578 61/88 (69%)
SLC25A6NP_001627.2 PTZ00169 3..298 CDD:240302 236/292 (81%)
Solcar 1 6..98 77/91 (85%)
Solcar 2 111..201 76/89 (85%)
Solcar 3 212..297 59/84 (70%)
Important for transport activity. /evidence=ECO:0000250|UniProtKB:P12235 235..240 4/4 (100%)
Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722 235..240 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 169 1.000 Domainoid score I3802
eggNOG 1 0.900 - - E1_KOG0749
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 488 1.000 Inparanoid score I1434
Isobase 1 0.950 - 0 Normalized mean entropy S337
OMA 1 1.010 - - QHG54049
OrthoDB 1 1.010 - - D440386at33208
OrthoFinder 1 1.000 - - FOG0000386
OrthoInspector 1 1.000 - - mtm8481
orthoMCL 1 0.900 - - OOG6_100505
Panther 1 1.100 - - LDO PTHR45635
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X286
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
1312.830

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