DRSC/TRiP Functional Genomics Resources

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Protein Alignment sesB and SLC25A5

DIOPT Version :9

Sequence 1:NP_727448.1 Gene:sesB / 32007 FlyBaseID:FBgn0003360 Length:312 Species:Drosophila melanogaster
Sequence 2:NP_001143.2 Gene:SLC25A5 / 292 HGNCID:10991 Length:298 Species:Homo sapiens


Alignment Length:292 Identity:238/292 - (81%)
Similarity:258/292 - (88%) Gaps:1/292 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 AVGFVKDFAAGGISAAVSKTAVAPIERVKLLLQVQHISKQISPDKQYKGMVDCFIRIPKEQGFSS 84
            ||.|.|||.|||::||:|||||||||||||||||||.||||:.||||||::||.:|||||||..|
Human     5 AVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69

  Fly    85 FWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFWRYFAGNLASGGAAGATSLCFVYPL 149
            ||||||||||||||||||||||||||||:|||||||.||||.|||||||||||||||||||||||
Human    70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLCFVYPL 134

  Fly   150 DFARTRLAADTGK-GGQREFTGLGNCLTKIFKSDGIVGLYRGFGVSVQGIIIYRAAYFGFYDTAR 213
            ||||||||||.|| |.:|||.|||:||.||:|||||.|||:||.|||||||||||||||.||||:
Human   135 DFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAK 199

  Fly   214 GMLPDPKNTPIYISWAIAQVVTTVAGIVSYPFDTVRRRMMMQSGRKATEVIYKNTLHCWATIAKQ 278
            |||||||||.|.|||.|||.||.|||:.||||||||||||||||||.|:::|..||.||..||:.
Human   200 GMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARD 264

  Fly   279 EGTGAFFKGAFSNILRGTGGAFVLVLYDEIKK 310
            ||..||||||:||:|||.||||||||||||||
Human   265 EGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKK 296

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sesBNP_727448.1 Mito_carr 19..116 CDD:278578 79/95 (83%)
PTZ00169 23..312 CDD:240302 236/289 (82%)
Mito_carr 124..220 CDD:278578 82/96 (85%)
Mito_carr 223..312 CDD:278578 65/88 (74%)
SLC25A5NP_001143.2 Mito_carr 6..101 CDD:278578 78/94 (83%)
Solcar 1 6..98 76/91 (84%)
PTZ00169 7..296 CDD:240302 234/288 (81%)
Mito_carr 109..206 CDD:278578 82/96 (85%)
Solcar 2 111..201 75/89 (84%)
Mito_carr 209..297 CDD:278578 65/88 (74%)
Solcar 3 212..297 64/85 (75%)
Important for transport activity. /evidence=ECO:0000250|UniProtKB:P12235 235..240 4/4 (100%)
Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722 235..240 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 169 1.000 Domainoid score I3802
eggNOG 1 0.900 - - E1_KOG0749
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 488 1.000 Inparanoid score I1434
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG54049
OrthoDB 1 1.010 - - D440386at33208
OrthoFinder 1 1.000 - - FOG0000386
OrthoInspector 1 1.000 - - mtm8481
orthoMCL 1 0.900 - - OOG6_100505
Panther 1 1.100 - - O PTHR45635
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R28
SonicParanoid 1 1.000 - - X286
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
1312.910

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