DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sesB and anc1

DIOPT Version :9

Sequence 1:	NP_727448.1	Gene:	sesB / 32007	FlyBaseID:	FBgn0003360	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_595323.1	Gene:	anc1 / 2540900	PomBaseID:	SPBC530.10c	Length:	322	Species:	Schizosaccharomyces pombe

Alignment Length:	316	Identity:	160/316 - (50%)
Similarity:	209/316 - (66%)	Gaps:	19/316 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ISASITSQSKMGKDFDAVGFVKDFAAGGISAAVSKTAVAPIERVKLLLQVQHISKQISPDK---Q 65
            ::|:..:::|...      |..||..||:||||||||.|||||||||:|.|  .:.|...:   :
pombe    14 VNANTITETKNST------FFFDFMMGGVSAAVSKTAAAPIERVKLLIQNQ--DEMIRAGRLSHR 70

  Fly    66 YKGMVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFWRYFAG 130
            |||:.:||.|...|:|..|.||||.|||:|||||||||||||||:|::| |...:...:.::|||
pombe    71 YKGIGECFKRTAAEEGVISLWRGNTANVLRYFPTQALNFAFKDKFKKMF-GYKKERDGYAKWFAG 134

  Fly   131 NLASGGAAGATSLCFVYPLDFARTRLAAD---TGKGGQREFTGLGNCLTKIFKSDGIVGLYRGFG 192
            ||||||||||.||.|||.||:||||||.|   ..|||:|:|.||.:...|.::|||:.|||||||
pombe   135 NLASGGAAGAASLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTYRSDGLRGLYRGFG 199

  Fly   193 VSVQGIIIYRAAYFGFYDTARG-MLPDPKNTPIYISWAIAQVVTTVAGIVSYPFDTVRRRMMMQS 256
            .||.||::||..|||.|||.:. :|..|.......|:.:...|||.:|:.|||.||:||||||.|
pombe   200 PSVVGIVVYRGLYFGMYDTLKPVVLVGPLEGNFLASFLLGWAVTTGSGVASYPLDTIRRRMMMTS 264

  Fly   257 GRKATEVIYKNTLHCWATIAKQEGTGAFFKGAFSNILRGTGGAFVLVLYDEIKKVL 312
            |.   .|.|.::..|...|..:||..:|||||.:|||||..||.||.:||:::.::
pombe   265 GE---AVKYSSSFECGRQILAKEGARSFFKGAGANILRGVAGAGVLSIYDQVQLLM 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sesB	NP_727448.1	Mito_carr	19..116	CDD:278578	58/99 (59%)
		PTZ00169	23..312	CDD:240302	158/295 (54%)
		Mito_carr	124..220	CDD:278578	58/99 (59%)
		Mito_carr	223..312	CDD:278578	40/88 (45%)
anc1	NP_595323.1	PTZ00169	23..317	CDD:240302	159/305 (52%)
		Mito_carr	23..123	CDD:278578	60/108 (56%)
		Mito_carr	<149..220	CDD:278578	42/70 (60%)
		Mito_carr	231..321	CDD:278578	40/90 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	119	1.000	Domainoid score	I1470
eggNOG	1	0.900	-	-		E1_KOG0749
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I626
OMA	1	1.010	-	-		QHG54049
OrthoFinder	1	1.000	-	-		FOG0000386
OrthoInspector	1	1.000	-	-		otm47027
orthoMCL	1	0.900	-	-		OOG6_100505
Panther	1	1.100	-	-	LDO	PTHR45635
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R28
SonicParanoid	1	1.000	-	-		X286
TreeFam	1	0.960	-	-
	13	12.860