Protein Alignment Rph and TCB1

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_014729.1
• Gene: TCB1 / 854253
• SGDID: S000005612
• Length: 1186
• Species: Saccharomyces cerevisiae
• Alignment Length: 263
• Identity: 61/263 - (23%)
• Similarity: 108/263 - (41%)
• Gaps: 64/263 - (24%)

  Fly   398 ITPEAHTKYTR-WQRTKTV-------HKTRNPE---FNETLQFVGVEPEELGNSLIYVALFDDDK 451
            |:.|...|:.: |...|.:       .|...||   :|:.:..|.|...||.:|.:||..|.||.
Yeast   823 ISKEDKAKFDQEWNEVKELEDMYSNRQKLDLPELLQYNQGVLAVTVLNGELPDSGLYVQAFFDDN 887

  Fly   452 YGHDFLGAAKV--------------------------------------CLSTVHSTSQ------ 472
             ||....:.::                                      |:..|...:|
Yeast   888 -GHPRFVSPRIPSRIVKNGWSGDVIIKELDKSITTFRVAKNKNYNRVEKCVCEVELPTQELVKNC 951

  Fly   473 -YRISVPLGVEDQYSNAAEMAQNW-P-NGKMLLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDP 534
             |:.|: |.:..:.|....:..:| | :.|.|.:....|....|.:..:...||:|.|.||.|||
Yeast   952 YYKPSI-LHLSGEGSAKLMLQISWFPIDTKQLPANDLITNSGDLTIMSRSAENLIASDLNGYSDP 1015

  Fly   535 FVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGS 599
            ::|..:..:  ::..:||.|..:||||.:|:|...:.: :.|| ::|.:.|.|.|...::|.:|:
Yeast  1016 YLKYYINNE--EDCAYKTKVVKKTLNPKWNDEGTIQIN-NRLN-DVLRIKVMDWDSTSADDTIGT 1076

  Fly   600 LQL 602
            .::
Yeast  1077 AEI 1079

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	25/134 (19%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	31/104 (30%)
TCB1	NP_014729.1	COG5038	1..1182	CDD:227371	61/263 (23%)