Protein Alignment Rph and Syt10

DIOPT Version :9

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_113854.1
• Gene: Syt10 / 60567
• RGDID: 62041
• Length: 523
• Species: Rattus norvegicus
• Alignment Length: 502
• Identity: 123/502 - (24%)
• Similarity: 201/502 - (40%)
• Gaps: 131/502 - (26%)

  Fly   162 MPRSASATPI--------------PNPGPGSMAGDTRAVQSCHATPTRPARVKKLTIRVNDSSSS 212
            :|:|.|:.|.              ..|.|.::   ..|::..|.:|..||
  Rat    96 LPQSISSAPTEVFETEEKKEVEENEKPAPKAI---EPAIKISHTSPDIPA--------------- 142

  Fly   213 SSGHSEPEDEVDTGVGIGVGVVGGGMAKGIASTRLQREDSFRLRAYGSIRSFIDGGERKLSNSFF 277
                     ||.|.:...:          |...|:||:.:             |.......|||
  Rat   143 ---------EVQTALKEHL----------IKHARVQRQTT-------------DPTSSSRHNSF- 174

  Fly   278 FNRQQSQRPSECPEYDSVSMSKLRRESSFLRRGSVSSSWSISDSSGSGSNNSGNSQTQSQYQQHQ 342
              |:...|.......| .||.    ....|:||...:|             .|..:.: .|:|..
  Rat   175 --RRHLPRQMNVSSVD-FSMG----TEPVLQRGETRTS-------------IGRIKPE-LYKQKS 218

  Fly   343 QQLQQHCRDPL--LGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCKLNIITPEAHTK 405
            ...:.:.:|.:  .|.|..|:.|......|...:::|.||||.|..|.:|||.|:.:: |:...|
  Rat   219 VDSEGNRKDDVKTCGKLNFALQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKIYLL-PDRKKK 282

  Fly   406 YTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYG-HDFLGAAKVCLSTVHS 469
            :    :|:...||.||.|:|..|| .|..::|.|..::.:::|.|::. ||.:|  :|.|..:.
  Rat   283 F----QTRVHRKTLNPLFDELFQF-PVVYDQLSNRKLHFSIYDFDRFSRHDMIG--EVILDNLF- 339

  Fly   470 TSQYRISVPLGVEDQYSNAAEMAQNWPN-----------GKMLLSLCYNTKRRALVVNVKQCINL 523
                          :.|:.:..|..|.:           |:::.||||......:.:.|.:|.||
  Rat   340 --------------EVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNL 390

  Fly   524 MAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLNKEMLILTVWDK 588
            .|||..|||||:||:.|..:..:.||.||:.|..||||:|||...|:..|.::::..|.:.|.|.
  Rat   391 KAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLCIAVMDY 455

  Fly   589 DLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEK----WHCL 631
            |....|:.:|..:.|..::|.....|.:.:.    :|.|    ||.|
  Rat   456 DRVGHNEVIGVCRTGLDAEGLGRDHWNEMLA----YHRKPITHWHPL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	PHD_SF	84..172	CDD:304600	4/23 (17%)
		C2A_Rabphilin_Doc2	354..477	CDD:176000	37/123 (30%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	46/135 (34%)
Syt10	NP_113854.1	Cysteine motif. /evidence=ECO:0000250|UniProtKB:O35681	13..35
		C2A_Synaptotagmin-1-5-6-9-10	231..356	CDD:176031	40/147 (27%)
		C2B_Synaptotagmin-3-5-6-9-10	365..498	CDD:176048	47/136 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910