Protein Alignment Rph and Syt6

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_038958948.1
• Gene: Syt6 / 60565
• RGDID: 62012
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 522
• Identity: 127/522 - (24%)
• Similarity: 212/522 - (40%)
• Gaps: 139/522 - (26%)

  Fly   146 WKKSGAWFFKGLPKYDMP---RSASATPIPNPGP---------GSMAGDTR----------AVQS 188
            ||.  .|         ||   :.||:....||..         |:||...:          ||:.
  Rat    81 WKL--CW---------MPWRNKEASSPSSANPASEILQSPSSRGNMADKLKDPSALGFLEAAVKI 134

  Fly   189 CHATPTRPARVK-----------KLTIRVNDSSSSSSGHSEPEDEVDTGVGIGVGVVGGGMAKGI 242
            .|.:|..||.|:           ||..:..:.:||:
  Rat   135 SHTSPDIPAEVQMSVKEHIMRHTKLQRQTTEPASST----------------------------- 170

  Fly   243 ASTRLQREDSFRLRAYGSIR-SFIDGGERKLSNSFFFNRQQSQRPSECPEYDSVSMSKLRRESSF 306
                  |..||:......:. |.:|.|              ::.|....| ...|:.:::.|  .
  Rat   171 ------RHTSFKRHLPRQMHVSSVDYG--------------NELPPAAAE-QPTSIGRIKPE--L 212

  Fly   307 LRRGSVSSSWSISDSSGSGSNNSGNSQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLD 371
            .::.||....:.|:::.|                        |     |.:..::.|.....:|.
  Rat   213 YKQKSVDGDEAKSEAAKS------------------------C-----GKINFSLRYDYESETLI 248

  Fly   372 CTMVRARDLPAMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEE 436
            ..:::|.||||.|..|.:|||.|:.:: |:...|.    :|:...||.||.|:|...| .|..||
  Rat   249 VRILKAFDLPAKDFCGSSDPYVKIYLL-PDRKCKL----QTRVHRKTLNPTFDENFHF-PVPYEE 307

  Fly   437 LGNSLIYVALFDDDKYG-HDFLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPNGKM 500
            |.:..:::::||.|::. ||.:|  :|.|..:...|.......:..:.||:.    :::...|::
  Rat   308 LADRKLHLSVFDFDRFSRHDMIG--EVILDNLFEASDLSRETSIWKDIQYAT----SESVDLGEI 366

  Fly   501 LLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNE 565
            :.||||......|.:.|.:|.||.|||..|.|||:||:.|..|..:.||.||::|..||||:|||
  Rat   367 MFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNE 431

  Fly   566 EFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHC 630
            ...|:..|.::::..|:::|.|.|....|:.:|..::|..::|.....|.:.:..|......|||
  Rat   432 AIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGISAEGLGRDHWNEMLAYPRKPIAHWHC 496

  Fly   631 LA 632
            ||
  Rat   497 LA 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710	7/28 (25%)
		C2A_Rabphilin_Doc2	354..477	CDD:176000	37/123 (30%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	46/131 (35%)
Syt6	XP_038958948.1	C2A_Synaptotagmin-1-5-6-9-10	231..355	CDD:176031	38/136 (28%)
		C2B_Synaptotagmin-3-5-6-9-10	364..497	CDD:176048	47/132 (36%)