Protein Alignment Rph and Doc2g

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_068563.2
• Gene: Doc2g / 60425
• MGIID: 1926250
• Length: 387
• Species: Mus musculus
• Alignment Length: 309
• Identity: 105/309 - (33%)
• Similarity: 162/309 - (52%)
• Gaps: 45/309 - (14%)

  Fly   354 LGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKT 418
            ||.||..:.:.|...:|.||..||:.|.. .|||..|.|.|.|:: |.| :|.:: .||:||..|
Mouse    84 LGTLEFTLLFDEDNSALHCTAHRAKGLKP-PAAGSVDTYVKANLL-PGA-SKASQ-LRTRTVRGT 144

  Fly   419 RNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYGHDFLG-------------------AAKVC- 463
            |.|.:.|||.:.|...::.|...:.:.:.:|.:......|                   :..:|
Mouse   145 REPVWEETLTYHGFTCQDAGRKTLRLCVCEDSRLRRRRRGPPLGELRVPLRKLVPNRARSFDICL 209

  Fly   464 -----------LSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPNGKMLLSLCYNTKRRALVVNV 517
                       |.|....|.|        |::...|....:.  .|::||||||:::|..|:|.|
Mouse   210 EKRKLTKRPKSLDTARGMSLY--------EEEEMEAEVFGEE--RGRILLSLCYSSERGGLLVGV 264

  Fly   518 KQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLNKEMLI 582
            .:|::|..||.||.|||||::.|.|.:.|..|:||||:.:||||.:||||::.....:|.::.|:
Mouse   265 LRCVHLAPMDANGYSDPFVRLFLHPSSGKKSKYKTSVRRKTLNPEFNEEFFYAGHREELAQKALL 329

  Fly   583 LTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHCL 631
            ::|||.|||.::||:|.:||..::.||||:.|.:|:...||..|.||.|
Mouse   330 VSVWDYDLGTADDFIGGVQLSGRASGERLRHWRECLGHCDHRLELWHLL 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	40/153 (26%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	61/131 (47%)
Doc2g	NP_068563.2	C2A_Rabphilin_Doc2	84..209	CDD:176000	35/128 (27%)
		C2	246..378	CDD:472691	61/131 (47%)